Phytochemical screening and inhibitory activity of oxalocalcic crystallization of Arbutus unedo L. leaves
The present study is focused on the experimental verification of the efficiency of Arbutus unedo L. leaves against the crystallization of calcium oxalate. The inhibition of crystallization has been studied in vitro with the absence and the presence of the different concentrations of the infusion and...
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Elsevier
2018-12-01
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| Series: | Heliyon |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844018342439 |
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| author | Rabie Kachkoul Tarik Sqalli Houssaini Radouane El Habbani Youssef Miyah Mohamed Mohim Anissa Lahrichi |
| author_facet | Rabie Kachkoul Tarik Sqalli Houssaini Radouane El Habbani Youssef Miyah Mohamed Mohim Anissa Lahrichi |
| author_sort | Rabie Kachkoul |
| collection | DOAJ |
| description | The present study is focused on the experimental verification of the efficiency of Arbutus unedo L. leaves against the crystallization of calcium oxalate. The inhibition of crystallization has been studied in vitro with the absence and the presence of the different concentrations of the infusion and hydroalcoholic extract of the plant. This study consists of measuring, using a UV-Visible spectrophotometer, the temporal evolution of the optical density at λ = 620 nm corresponding to the crystals formation. The latter have been characterized by microscopic observation using an optical microscope, and by Fourier Transform Infrared Spectroscopy (FT-IR). The results suggest a greater effectiveness of the plant infusion with respect to the hydroalcoholic extract against crystallization or nucleation at percentages of 69.41 ± 0.24 or 19.76 ± 0.27% and at 93.92 ± 2.61 and 45.16 ± 3.06% against the aggregation, for both the infusion and the hydroalcoholic extract respectively. A. unedo leaves is a very promising and effective remedy against the crystallization of calcium oxalate and especially in the aggregation stage. |
| first_indexed | 2024-12-21T17:25:13Z |
| format | Article |
| id | doaj.art-aa63a060c2f9466d8a037106fa77176a |
| institution | Directory Open Access Journal |
| issn | 2405-8440 |
| language | English |
| last_indexed | 2024-12-21T17:25:13Z |
| publishDate | 2018-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Heliyon |
| spelling | doaj.art-aa63a060c2f9466d8a037106fa77176a2022-12-21T18:56:04ZengElsevierHeliyon2405-84402018-12-01412e01011Phytochemical screening and inhibitory activity of oxalocalcic crystallization of Arbutus unedo L. leavesRabie Kachkoul0Tarik Sqalli Houssaini1Radouane El Habbani2Youssef Miyah3Mohamed Mohim4Anissa Lahrichi5Laboratory of Biochemistry, Faculty of Medicine and Pharmacy, University Sidi Mohammed Ben Abdellah, BP 1893, Km 22, Road of Sidi Harazem, Fez, Morocco; Corresponding author.Department of Nephrology, University Hospital Hassan II, BP 1835, Atlas, Road of Sidi Harazem, Fez, Morocco; Laboratory of Molecular Bases in Human Pathology and Therapeutic Tools, Faculty of Medicine and Pharmacy, University Sidi Mohammed Ben Abdellah, BP 1893, Km 22, Road of Sidi Harazem, Fez, MoroccoLaboratory of Biochemistry, Faculty of Medicine and Pharmacy, University Sidi Mohammed Ben Abdellah, BP 1893, Km 22, Road of Sidi Harazem, Fez, MoroccoLaboratory of Biochemistry, Faculty of Medicine and Pharmacy, University Sidi Mohammed Ben Abdellah, BP 1893, Km 22, Road of Sidi Harazem, Fez, MoroccoLaboratory of Molecular Bases in Human Pathology and Therapeutic Tools, Faculty of Medicine and Pharmacy, University Sidi Mohammed Ben Abdellah, BP 1893, Km 22, Road of Sidi Harazem, Fez, MoroccoLaboratory of Biochemistry, Faculty of Medicine and Pharmacy, University Sidi Mohammed Ben Abdellah, BP 1893, Km 22, Road of Sidi Harazem, Fez, MoroccoThe present study is focused on the experimental verification of the efficiency of Arbutus unedo L. leaves against the crystallization of calcium oxalate. The inhibition of crystallization has been studied in vitro with the absence and the presence of the different concentrations of the infusion and hydroalcoholic extract of the plant. This study consists of measuring, using a UV-Visible spectrophotometer, the temporal evolution of the optical density at λ = 620 nm corresponding to the crystals formation. The latter have been characterized by microscopic observation using an optical microscope, and by Fourier Transform Infrared Spectroscopy (FT-IR). The results suggest a greater effectiveness of the plant infusion with respect to the hydroalcoholic extract against crystallization or nucleation at percentages of 69.41 ± 0.24 or 19.76 ± 0.27% and at 93.92 ± 2.61 and 45.16 ± 3.06% against the aggregation, for both the infusion and the hydroalcoholic extract respectively. A. unedo leaves is a very promising and effective remedy against the crystallization of calcium oxalate and especially in the aggregation stage.http://www.sciencedirect.com/science/article/pii/S2405844018342439BiochemistryPharmaceutical sciencePlant biology |
| spellingShingle | Rabie Kachkoul Tarik Sqalli Houssaini Radouane El Habbani Youssef Miyah Mohamed Mohim Anissa Lahrichi Phytochemical screening and inhibitory activity of oxalocalcic crystallization of Arbutus unedo L. leaves Heliyon Biochemistry Pharmaceutical science Plant biology |
| title | Phytochemical screening and inhibitory activity of oxalocalcic crystallization of Arbutus unedo L. leaves |
| title_full | Phytochemical screening and inhibitory activity of oxalocalcic crystallization of Arbutus unedo L. leaves |
| title_fullStr | Phytochemical screening and inhibitory activity of oxalocalcic crystallization of Arbutus unedo L. leaves |
| title_full_unstemmed | Phytochemical screening and inhibitory activity of oxalocalcic crystallization of Arbutus unedo L. leaves |
| title_short | Phytochemical screening and inhibitory activity of oxalocalcic crystallization of Arbutus unedo L. leaves |
| title_sort | phytochemical screening and inhibitory activity of oxalocalcic crystallization of arbutus unedo l leaves |
| topic | Biochemistry Pharmaceutical science Plant biology |
| url | http://www.sciencedirect.com/science/article/pii/S2405844018342439 |
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