A new method of N to C sequential ligation using thioacid capture ligation and native chemical ligation
Sequential peptide ligation strategy becomes more and more important in large protein or long peptides chemical synthesis due to the limited peptide/protein size obtained by solid phase synthesis of individual peptides or even one-step peptide ligation. Herein, we developed an alternative method whi...
Main Authors: | Wen Hou, Lei Liu, Xiaohong Zhang, Chuanfa Liu |
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Format: | Article |
Language: | English |
Published: |
The Royal Society
2018-01-01
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Series: | Royal Society Open Science |
Subjects: | |
Online Access: | https://royalsocietypublishing.org/doi/pdf/10.1098/rsos.172455 |
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