2-Aminoethoxydiphenyl borate activates the human mechano-gated KCNK channels KCNK 2 (TREK-1), KCNK 4 (TRAAK) and KCNK 10 (TREK-2).

2-Aminoethoxydiphenyl borate activates the human mechano-gated KCNK channels KCNK 2 (TREK-1), KCNK 4 (TRAAK) and KCNK 10 (TREK-2).

Abstract: Two-pore domain K+ (KCNK, K2P) channels underlie the leak (background) potassium conductance in many types of excitable cells. They oppose membrane depolarization and cell excitability. These channels have been reported to be modulated by several physical and chemical stimuli. The compound...

Celý popis

Podrobná bibliografie
Hlavní autoři: Leopoldo Raul Beltran, Madeline eBeltran, Ainhara eAguado, Guenter eGisselmann, Hanns eHatt
Médium: Článek
Jazyk:English
Vydáno: Frontiers Media S.A. 2013-05-01
Edice:Frontiers in Pharmacology
Témata:
2-APB
KCNK channels
TREK
Xenopus oocytes
two-electrode voltage clamp
On-line přístup:http://journal.frontiersin.org/Journal/10.3389/fphar.2013.00063/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphar.2013.00063/full

Podobné jednotky