Sensitization to Fragrance mix-1 in Patients with Contact Dermatitis in Nord-East of Italy: 1996–2016 Time Trend and Gender Effect
(1) Background: Fragrance sensitization is common in Italy and their constituents are used in many cosmetics and detergents. The objective of the study was to analyze the temporal trend of sensitivity to fragrance mix-1 in northeastern Italy and to evaluate gender differences; (2) Methods: From 1996...
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| Format: | Article |
| Language: | English |
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MDPI AG
2019-03-01
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| Series: | Cosmetics |
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| Online Access: | https://www.mdpi.com/2079-9284/6/2/22 |
| _version_ | 1819263835691810816 |
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| author | Francesca Larese Filon Marcella Mauro |
| author_facet | Francesca Larese Filon Marcella Mauro |
| author_sort | Francesca Larese Filon |
| collection | DOAJ |
| description | (1) Background: Fragrance sensitization is common in Italy and their constituents are used in many cosmetics and detergents. The objective of the study was to analyze the temporal trend of sensitivity to fragrance mix-1 in northeastern Italy and to evaluate gender differences; (2) Methods: From 1996 to 2016, 27,381 consecutive patients with suspected allergic contact dermatitis were patch tested. Individual characteristics were collected through a standardized questionnaire in six departments of dermatology or occupational medicine; (3) Results: The overall prevalence of sensitization to fragrance mix-1 was 7.3%; the prevalence was significantly higher in women (7.7%) than in men (6.3%). From 1996 to 2016, we observed an increase of this sensitization, ranging from 6.2% to 7.7% in males and from 7.2% to 9.1% in females; (4) Conclusions: Our study showed that contact allergy to fragrance mix-1 is important in both sexes and prevalence is increasing over time, despite the introduction of new fragrances with lower sensitization potential. There is the need to reduce the use of fragrances mix-1 to stop the increase of sensitization in exposed subjects. |
| first_indexed | 2024-12-23T20:19:54Z |
| format | Article |
| id | doaj.art-aa68d18ac69e463a9c415a1fef77e946 |
| institution | Directory Open Access Journal |
| issn | 2079-9284 |
| language | English |
| last_indexed | 2024-12-23T20:19:54Z |
| publishDate | 2019-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Cosmetics |
| spelling | doaj.art-aa68d18ac69e463a9c415a1fef77e9462022-12-21T17:32:35ZengMDPI AGCosmetics2079-92842019-03-01622210.3390/cosmetics6020022cosmetics6020022Sensitization to Fragrance mix-1 in Patients with Contact Dermatitis in Nord-East of Italy: 1996–2016 Time Trend and Gender EffectFrancesca Larese Filon0Marcella Mauro1Clinical Unit of Occupational Medicine, 32124 Trieste, ItalyClinical Unit of Occupational Medicine, 32124 Trieste, Italy(1) Background: Fragrance sensitization is common in Italy and their constituents are used in many cosmetics and detergents. The objective of the study was to analyze the temporal trend of sensitivity to fragrance mix-1 in northeastern Italy and to evaluate gender differences; (2) Methods: From 1996 to 2016, 27,381 consecutive patients with suspected allergic contact dermatitis were patch tested. Individual characteristics were collected through a standardized questionnaire in six departments of dermatology or occupational medicine; (3) Results: The overall prevalence of sensitization to fragrance mix-1 was 7.3%; the prevalence was significantly higher in women (7.7%) than in men (6.3%). From 1996 to 2016, we observed an increase of this sensitization, ranging from 6.2% to 7.7% in males and from 7.2% to 9.1% in females; (4) Conclusions: Our study showed that contact allergy to fragrance mix-1 is important in both sexes and prevalence is increasing over time, despite the introduction of new fragrances with lower sensitization potential. There is the need to reduce the use of fragrances mix-1 to stop the increase of sensitization in exposed subjects.https://www.mdpi.com/2079-9284/6/2/22fragrance mix-1patch testepidemiologyallergic contact dermatitisgender |
| spellingShingle | Francesca Larese Filon Marcella Mauro Sensitization to Fragrance mix-1 in Patients with Contact Dermatitis in Nord-East of Italy: 1996–2016 Time Trend and Gender Effect Cosmetics fragrance mix-1 patch test epidemiology allergic contact dermatitis gender |
| title | Sensitization to Fragrance mix-1 in Patients with Contact Dermatitis in Nord-East of Italy: 1996–2016 Time Trend and Gender Effect |
| title_full | Sensitization to Fragrance mix-1 in Patients with Contact Dermatitis in Nord-East of Italy: 1996–2016 Time Trend and Gender Effect |
| title_fullStr | Sensitization to Fragrance mix-1 in Patients with Contact Dermatitis in Nord-East of Italy: 1996–2016 Time Trend and Gender Effect |
| title_full_unstemmed | Sensitization to Fragrance mix-1 in Patients with Contact Dermatitis in Nord-East of Italy: 1996–2016 Time Trend and Gender Effect |
| title_short | Sensitization to Fragrance mix-1 in Patients with Contact Dermatitis in Nord-East of Italy: 1996–2016 Time Trend and Gender Effect |
| title_sort | sensitization to fragrance mix 1 in patients with contact dermatitis in nord east of italy 1996 2016 time trend and gender effect |
| topic | fragrance mix-1 patch test epidemiology allergic contact dermatitis gender |
| url | https://www.mdpi.com/2079-9284/6/2/22 |
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