Clinical significance of ocular surface analyzer for meibomian gland dysfunction in diabetic patients
AIM: To analyze the application value of ocular surface analyzer in meibomian gland dysfunction(MGD)of patients with diabetes mellitus(DM).METHODS: Patients with type 2 diabetes mellitus(T2DM)admitted to Hebei Eye Hospital between May 2017 and May 2021 were selected. They were divided into three gro...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Press of International Journal of Ophthalmology (IJO PRESS)
2022-12-01
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| Series: | Guoji Yanke Zazhi |
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| Online Access: | http://ies.ijo.cn/cn_publish/2022/12/202212021.pdf |
| _version_ | 1811323101301964800 |
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| author | Xin Wang Qin-Ying Li Li-Fei Yuan Li-Fei Wang |
| author_facet | Xin Wang Qin-Ying Li Li-Fei Yuan Li-Fei Wang |
| author_sort | Xin Wang |
| collection | DOAJ |
| description | AIM: To analyze the application value of ocular surface analyzer in meibomian gland dysfunction(MGD)of patients with diabetes mellitus(DM).METHODS: Patients with type 2 diabetes mellitus(T2DM)admitted to Hebei Eye Hospital between May 2017 and May 2021 were selected. They were divided into three groups according to the course of disease, with 37 cases in short-term goup(DM course <5a), 31 cases in medium-term group(5a< DM course <10a)and 34 cases in long-term group(DM course ≥10a). Meanwhile, patients without diabetes mellitus(DM)were selected as the control group. The ocular surface disease index(OSDI), tear meniscus height(TMH), non-invasive first tear film break-up time(NIBUT), lipid layer thickness(LLT)and absence of meibomian gland were compared among the four groups.RESULTS: Patients with different course of DM had significantly higher OSDI than the control group(all P<0.05), and their TMH, first NIBUT, and mean NIBUT were significantly lower than those of the control group(P<0.05). With the progression of DM, the OSDI gradually increased, while TMH, first NIBUT and mean NIBUT decreased. The grades of LLT and absence of meibomian gland were different in the four groups(P<0.05). As DM progressed, patients with grade 1 LLT increased, while patients with grade 2 LLT decreased. Moreover, patients with grade 0 absence of meibomian gland decreased, while those with grade 1 increased.CONCLUSION: Ocular surface analyzer is helpful for evaluating MGD in patients with DM. It can accurately and objectively evaluate the function and morphology of meibomian gland, which is beneficial to early diagnosis and subsequent treatment of MGD in patients with DM. |
| first_indexed | 2024-04-13T13:48:08Z |
| format | Article |
| id | doaj.art-aa6b1a67dd7e4dbf999b89a09b9cc1fd |
| institution | Directory Open Access Journal |
| issn | 1672-5123 |
| language | English |
| last_indexed | 2024-04-13T13:48:08Z |
| publishDate | 2022-12-01 |
| publisher | Press of International Journal of Ophthalmology (IJO PRESS) |
| record_format | Article |
| series | Guoji Yanke Zazhi |
| spelling | doaj.art-aa6b1a67dd7e4dbf999b89a09b9cc1fd2022-12-22T02:44:25ZengPress of International Journal of Ophthalmology (IJO PRESS)Guoji Yanke Zazhi1672-51232022-12-0122122044204810.3980/j.issn.1672-5123.2022.12.21202212021Clinical significance of ocular surface analyzer for meibomian gland dysfunction in diabetic patientsXin Wang0Qin-Ying Li1Li-Fei Yuan2Li-Fei Wang3Hebei Eye Hospital, Xingtai 054000, Hebei Province, ChinaHebei Eye Hospital, Xingtai 054000, Hebei Province, ChinaHebei Eye Hospital, Xingtai 054000, Hebei Province, ChinaHebei Eye Hospital, Xingtai 054000, Hebei Province, ChinaAIM: To analyze the application value of ocular surface analyzer in meibomian gland dysfunction(MGD)of patients with diabetes mellitus(DM).METHODS: Patients with type 2 diabetes mellitus(T2DM)admitted to Hebei Eye Hospital between May 2017 and May 2021 were selected. They were divided into three groups according to the course of disease, with 37 cases in short-term goup(DM course <5a), 31 cases in medium-term group(5a< DM course <10a)and 34 cases in long-term group(DM course ≥10a). Meanwhile, patients without diabetes mellitus(DM)were selected as the control group. The ocular surface disease index(OSDI), tear meniscus height(TMH), non-invasive first tear film break-up time(NIBUT), lipid layer thickness(LLT)and absence of meibomian gland were compared among the four groups.RESULTS: Patients with different course of DM had significantly higher OSDI than the control group(all P<0.05), and their TMH, first NIBUT, and mean NIBUT were significantly lower than those of the control group(P<0.05). With the progression of DM, the OSDI gradually increased, while TMH, first NIBUT and mean NIBUT decreased. The grades of LLT and absence of meibomian gland were different in the four groups(P<0.05). As DM progressed, patients with grade 1 LLT increased, while patients with grade 2 LLT decreased. Moreover, patients with grade 0 absence of meibomian gland decreased, while those with grade 1 increased.CONCLUSION: Ocular surface analyzer is helpful for evaluating MGD in patients with DM. It can accurately and objectively evaluate the function and morphology of meibomian gland, which is beneficial to early diagnosis and subsequent treatment of MGD in patients with DM.http://ies.ijo.cn/cn_publish/2022/12/202212021.pdfmeibomian gland dysfunctionocular surface analyzerdiabetes mellitustear filmlipid layer |
| spellingShingle | Xin Wang Qin-Ying Li Li-Fei Yuan Li-Fei Wang Clinical significance of ocular surface analyzer for meibomian gland dysfunction in diabetic patients Guoji Yanke Zazhi meibomian gland dysfunction ocular surface analyzer diabetes mellitus tear film lipid layer |
| title | Clinical significance of ocular surface analyzer for meibomian gland dysfunction in diabetic patients |
| title_full | Clinical significance of ocular surface analyzer for meibomian gland dysfunction in diabetic patients |
| title_fullStr | Clinical significance of ocular surface analyzer for meibomian gland dysfunction in diabetic patients |
| title_full_unstemmed | Clinical significance of ocular surface analyzer for meibomian gland dysfunction in diabetic patients |
| title_short | Clinical significance of ocular surface analyzer for meibomian gland dysfunction in diabetic patients |
| title_sort | clinical significance of ocular surface analyzer for meibomian gland dysfunction in diabetic patients |
| topic | meibomian gland dysfunction ocular surface analyzer diabetes mellitus tear film lipid layer |
| url | http://ies.ijo.cn/cn_publish/2022/12/202212021.pdf |
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