Sequence-selective encapsulation and protection of long peptides by a self-assembled FeII8L6 cubic cage
One of the challenges of synthetic self-assembled capsules is achieving selective recognition of specific cargoes. Here, authors synthesize a self-assembled porphyrin cubic cage that is capable of sequestering imidazole and thiazole-containing small molecules and peptides, protecting them from prote...
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Format: | Article |
Language: | English |
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Nature Portfolio
2017-03-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/ncomms14882 |
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author | Jesús Mosquera Bartosz Szyszko Sarah K. Y. Ho Jonathan R. Nitschke |
author_facet | Jesús Mosquera Bartosz Szyszko Sarah K. Y. Ho Jonathan R. Nitschke |
author_sort | Jesús Mosquera |
collection | DOAJ |
description | One of the challenges of synthetic self-assembled capsules is achieving selective recognition of specific cargoes. Here, authors synthesize a self-assembled porphyrin cubic cage that is capable of sequestering imidazole and thiazole-containing small molecules and peptides, protecting them from proteolysis. |
first_indexed | 2024-12-19T04:55:16Z |
format | Article |
id | doaj.art-aa6b5f198c7d4869a569764651de33d1 |
institution | Directory Open Access Journal |
issn | 2041-1723 |
language | English |
last_indexed | 2024-12-19T04:55:16Z |
publishDate | 2017-03-01 |
publisher | Nature Portfolio |
record_format | Article |
series | Nature Communications |
spelling | doaj.art-aa6b5f198c7d4869a569764651de33d12022-12-21T20:35:14ZengNature PortfolioNature Communications2041-17232017-03-01811610.1038/ncomms14882Sequence-selective encapsulation and protection of long peptides by a self-assembled FeII8L6 cubic cageJesús Mosquera0Bartosz Szyszko1Sarah K. Y. Ho2Jonathan R. Nitschke3Department of Chemistry, University of CambridgeDepartment of Chemistry, University of CambridgeDepartment of Chemistry, University of CambridgeDepartment of Chemistry, University of CambridgeOne of the challenges of synthetic self-assembled capsules is achieving selective recognition of specific cargoes. Here, authors synthesize a self-assembled porphyrin cubic cage that is capable of sequestering imidazole and thiazole-containing small molecules and peptides, protecting them from proteolysis.https://doi.org/10.1038/ncomms14882 |
spellingShingle | Jesús Mosquera Bartosz Szyszko Sarah K. Y. Ho Jonathan R. Nitschke Sequence-selective encapsulation and protection of long peptides by a self-assembled FeII8L6 cubic cage Nature Communications |
title | Sequence-selective encapsulation and protection of long peptides by a self-assembled FeII8L6 cubic cage |
title_full | Sequence-selective encapsulation and protection of long peptides by a self-assembled FeII8L6 cubic cage |
title_fullStr | Sequence-selective encapsulation and protection of long peptides by a self-assembled FeII8L6 cubic cage |
title_full_unstemmed | Sequence-selective encapsulation and protection of long peptides by a self-assembled FeII8L6 cubic cage |
title_short | Sequence-selective encapsulation and protection of long peptides by a self-assembled FeII8L6 cubic cage |
title_sort | sequence selective encapsulation and protection of long peptides by a self assembled feii8l6 cubic cage |
url | https://doi.org/10.1038/ncomms14882 |
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