Impaired maturation of serotonergic function in the dentate gyrus associated with epilepsy

Impaired maturation of serotonergic function in the dentate gyrus associated with epilepsy

Temporal lobe epilepsy is believed to develop after an initial precipitating injury, usually suffered in childhood or adolescence, and aspects include impaired maturation of the hippocampus, and specifically the dentate gyrus. The dentate gyrus receives a major serotonergic input from the brainstem...

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Bibliographic Details
Main Authors: Kate Elizabeth Gilling, Frank Oltmanns, Joachim Behr
Format: Article
Language:English
Published: Elsevier 2013-02-01
Series:Neurobiology of Disease
Subjects:
Serotonin
Dentate gyrus
Maturation
Temporal lobe epilepsy
Synaptic plasticity
5-HT1A receptor
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996112003403

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