Resting mitochondrial complex I from Drosophila melanogaster adopts a helix-locked state

Resting mitochondrial complex I from Drosophila melanogaster adopts a helix-locked state

Respiratory complex I is a proton-pumping oxidoreductase key to bioenergetic metabolism. Biochemical studies have found a divide in the behavior of complex I in metazoans that aligns with the evolutionary split between Protostomia and Deuterostomia. Complex I from Deuterostomia including mammals can...

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Bibliographic Details
Main Authors: Abhilash Padavannil, Anjaneyulu Murari, Shauna-Kay Rhooms, Edward Owusu-Ansah, James A Letts
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2023-03-01
Series:eLife
Subjects:
mitochondria
complex I
single particle cryoEM
electron transport chain
respiration
Online Access:https://elifesciences.org/articles/84415

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