Time and Antigen-Stimulation History Influence Memory CD8 T Cell Bystander Responses
Memory CD8 T cells can be activated and induced to produce cytokines and increase stores of cytolytic proteins not only in response to cognate antigen (Ag) but also in response to inflammatory cytokines (bystander responses). Importantly, bystander memory CD8 T cell functions have been shown to be d...
Main Authors: | Matthew D. Martin, Qiang Shan, Hai-Hui Xue, Vladimir P. Badovinac |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2017-06-01
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Series: | Frontiers in Immunology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/article/10.3389/fimmu.2017.00634/full |
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