Evaluation of the effect of pre-operative over-fasting on post-operative vomiting in children undergoing bone marrow aspiration at a tertiary care setting in Sri Lanka: A prospective cohort study
Background and Aims: Non-adherence to standard fasting guidelines may result in perioperative complications. We aimed to determine the association between pre-operative over-fasting and post-operative vomiting amongst children undergoing bone marrow aspiration under general anaesthesia. Methods: A p...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2018-01-01
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| Series: | Indian Journal of Anaesthesia |
| Subjects: | |
| Online Access: | http://www.ijaweb.org/article.asp?issn=0019-5049;year=2018;volume=62;issue=5;spage=366;epage=370;aulast=Jayasinghe |
| _version_ | 1819182926914387968 |
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| author | Vidura Jayasinghe P K Buddhika Mahesh C M D Sooriaarachchi Jimutha Jayalath Weranga Karunarathne S N Liyanage |
| author_facet | Vidura Jayasinghe P K Buddhika Mahesh C M D Sooriaarachchi Jimutha Jayalath Weranga Karunarathne S N Liyanage |
| author_sort | Vidura Jayasinghe |
| collection | DOAJ |
| description | Background and Aims: Non-adherence to standard fasting guidelines may result in perioperative complications. We aimed to determine the association between pre-operative over-fasting and post-operative vomiting amongst children undergoing bone marrow aspiration under general anaesthesia. Methods: A prospective cohort study was conducted from May 2015 to April 2016 in children undergoing bone marrow aspiration under general anaesthesia and their caregivers. Children fasted for ≥3 hours from last clear fluid intake constituted the exposed group (n = 202) while children fasting for <3 h constituted the non-exposed group (n = 202). The primary outcome was the development of post-operative vomiting during the 6 h following induction of anaesthesia. The awareness of the caregiver regarding the importance of keeping the child fasting before anaesthesia was evaluated. Results: The mean (standard deviation) duration time of fasting of the exposed and non-exposed groups were 7.2 (2.4) and 2.2 (0.3) h, respectively. Thirty-two (15.8%) children in the exposed group and 17 (8.4%) children in the non-exposed group developed post-operative vomiting. The relative risk of developing post-operative vomiting amongst over-fasting children was 1.9 (95% confidence interval [CI] = 1.1–3.3, P = 0.02), while adjusting to the age, it was 2.1 (95% CI = 1.1–4). Significantly more caregivers were clear about the fasting advice in the non-exposed group than in the exposed group (P < 0.001). Conclusion: Over-fasting is a significant risk factor to develop post-operative vomiting in paediatric anaesthetic practice. |
| first_indexed | 2024-12-22T22:53:54Z |
| format | Article |
| id | doaj.art-aa84523dea134351a1ab0d1bbb17de4d |
| institution | Directory Open Access Journal |
| issn | 0019-5049 0976-2817 |
| language | English |
| last_indexed | 2024-12-22T22:53:54Z |
| publishDate | 2018-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Anaesthesia |
| spelling | doaj.art-aa84523dea134351a1ab0d1bbb17de4d2022-12-21T18:09:53ZengWolters Kluwer Medknow PublicationsIndian Journal of Anaesthesia0019-50490976-28172018-01-0162536637010.4103/ija.IJA_727_17Evaluation of the effect of pre-operative over-fasting on post-operative vomiting in children undergoing bone marrow aspiration at a tertiary care setting in Sri Lanka: A prospective cohort studyVidura JayasingheP K Buddhika MaheshC M D SooriaarachchiJimutha JayalathWeranga KarunarathneS N LiyanageBackground and Aims: Non-adherence to standard fasting guidelines may result in perioperative complications. We aimed to determine the association between pre-operative over-fasting and post-operative vomiting amongst children undergoing bone marrow aspiration under general anaesthesia. Methods: A prospective cohort study was conducted from May 2015 to April 2016 in children undergoing bone marrow aspiration under general anaesthesia and their caregivers. Children fasted for ≥3 hours from last clear fluid intake constituted the exposed group (n = 202) while children fasting for <3 h constituted the non-exposed group (n = 202). The primary outcome was the development of post-operative vomiting during the 6 h following induction of anaesthesia. The awareness of the caregiver regarding the importance of keeping the child fasting before anaesthesia was evaluated. Results: The mean (standard deviation) duration time of fasting of the exposed and non-exposed groups were 7.2 (2.4) and 2.2 (0.3) h, respectively. Thirty-two (15.8%) children in the exposed group and 17 (8.4%) children in the non-exposed group developed post-operative vomiting. The relative risk of developing post-operative vomiting amongst over-fasting children was 1.9 (95% confidence interval [CI] = 1.1–3.3, P = 0.02), while adjusting to the age, it was 2.1 (95% CI = 1.1–4). Significantly more caregivers were clear about the fasting advice in the non-exposed group than in the exposed group (P < 0.001). Conclusion: Over-fasting is a significant risk factor to develop post-operative vomiting in paediatric anaesthetic practice.http://www.ijaweb.org/article.asp?issn=0019-5049;year=2018;volume=62;issue=5;spage=366;epage=370;aulast=JayasingheCaregiverfastinggeneral anaesthesiapaediatricvomiting |
| spellingShingle | Vidura Jayasinghe P K Buddhika Mahesh C M D Sooriaarachchi Jimutha Jayalath Weranga Karunarathne S N Liyanage Evaluation of the effect of pre-operative over-fasting on post-operative vomiting in children undergoing bone marrow aspiration at a tertiary care setting in Sri Lanka: A prospective cohort study Indian Journal of Anaesthesia Caregiver fasting general anaesthesia paediatric vomiting |
| title | Evaluation of the effect of pre-operative over-fasting on post-operative vomiting in children undergoing bone marrow aspiration at a tertiary care setting in Sri Lanka: A prospective cohort study |
| title_full | Evaluation of the effect of pre-operative over-fasting on post-operative vomiting in children undergoing bone marrow aspiration at a tertiary care setting in Sri Lanka: A prospective cohort study |
| title_fullStr | Evaluation of the effect of pre-operative over-fasting on post-operative vomiting in children undergoing bone marrow aspiration at a tertiary care setting in Sri Lanka: A prospective cohort study |
| title_full_unstemmed | Evaluation of the effect of pre-operative over-fasting on post-operative vomiting in children undergoing bone marrow aspiration at a tertiary care setting in Sri Lanka: A prospective cohort study |
| title_short | Evaluation of the effect of pre-operative over-fasting on post-operative vomiting in children undergoing bone marrow aspiration at a tertiary care setting in Sri Lanka: A prospective cohort study |
| title_sort | evaluation of the effect of pre operative over fasting on post operative vomiting in children undergoing bone marrow aspiration at a tertiary care setting in sri lanka a prospective cohort study |
| topic | Caregiver fasting general anaesthesia paediatric vomiting |
| url | http://www.ijaweb.org/article.asp?issn=0019-5049;year=2018;volume=62;issue=5;spage=366;epage=370;aulast=Jayasinghe |
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