Phytochemicals from Indian Ethnomedicines: Promising Prospects for the Management of Oxidative Stress and Cancer
Oxygen is indispensable for most organisms on the earth because of its role in respiration. However, it is also associated with several unwanted effects which may sometimes prove fatal in the long run. Such effects are more evident in cells exposed to strong oxidants containing reactive oxygen speci...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2021-10-01
|
| Series: | Antioxidants |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2076-3921/10/10/1606 |
| _version_ | 1797515446374629376 |
|---|---|
| author | Nishat Fatima Syed Shabihe Raza Baqri Ahmad Alsulimani Sharmila Fagoonee Petr Slama Kavindra Kumar Kesari Shubhadeep Roychoudhury Shafiul Haque |
| author_facet | Nishat Fatima Syed Shabihe Raza Baqri Ahmad Alsulimani Sharmila Fagoonee Petr Slama Kavindra Kumar Kesari Shubhadeep Roychoudhury Shafiul Haque |
| author_sort | Nishat Fatima |
| collection | DOAJ |
| description | Oxygen is indispensable for most organisms on the earth because of its role in respiration. However, it is also associated with several unwanted effects which may sometimes prove fatal in the long run. Such effects are more evident in cells exposed to strong oxidants containing reactive oxygen species (ROS). The adverse outcomes of oxidative metabolism are referred to as oxidative stress, which is a staple theme in contemporary medical research. Oxidative stress leads to plasma membrane disruption through lipid peroxidation and has several other deleterious effects. A large body of literature suggests the involvement of ROS in cancer, ageing, and several other health hazards of the modern world. Plant-based cures for these conditions are desperately sought after as supposedly safer alternatives to mainstream medicines. Phytochemicals, which constitute a diverse group of plant-based substances with varying roles in oxidative reactions of the body, are implicated in the treatment of cancer, aging, and all other ROS-induced anomalies. This review presents a summary of important phytochemicals extracted from medicinal plants which are a part of Indian ethnomedicine and Ayurveda and describes their possible therapeutic significance. |
| first_indexed | 2024-03-10T06:45:36Z |
| format | Article |
| id | doaj.art-aa8afe29ef934ab7a71350a36adb7366 |
| institution | Directory Open Access Journal |
| issn | 2076-3921 |
| language | English |
| last_indexed | 2024-03-10T06:45:36Z |
| publishDate | 2021-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Antioxidants |
| spelling | doaj.art-aa8afe29ef934ab7a71350a36adb73662023-11-22T17:16:38ZengMDPI AGAntioxidants2076-39212021-10-011010160610.3390/antiox10101606Phytochemicals from Indian Ethnomedicines: Promising Prospects for the Management of Oxidative Stress and CancerNishat Fatima0Syed Shabihe Raza Baqri1Ahmad Alsulimani2Sharmila Fagoonee3Petr Slama4Kavindra Kumar Kesari5Shubhadeep Roychoudhury6Shafiul Haque7Department of Chemistry, Shia PG College, Lucknow 226003, IndiaDepartment of Zoology, Shia PG College, Lucknow 226003, IndiaMedical Laboratory Technology Department, College of Applied Medical Sciences, Jazan University, Jazan 45142, Saudi ArabiaInstitute of Biostructure and Bioimaging (CNR), Molecular Biotechnology Center, 10124 Turin, ItalyDepartment of Animal Morphology, Physiology and Genetics, Faculty of AgriSciences, Mendel University in Brno, 61300 Brno, Czech RepublicDepartment of Applied Physics, School of Science, Aalto University, 00076 Espoo, FinlandDepartment of Life Science and Bioinformatics, Assam University, Silchar 788011, IndiaResearch and Scientific Studies Unit, College of Nursing and Allied Health Sciences, Jazan University, Jazan 45142, Saudi ArabiaOxygen is indispensable for most organisms on the earth because of its role in respiration. However, it is also associated with several unwanted effects which may sometimes prove fatal in the long run. Such effects are more evident in cells exposed to strong oxidants containing reactive oxygen species (ROS). The adverse outcomes of oxidative metabolism are referred to as oxidative stress, which is a staple theme in contemporary medical research. Oxidative stress leads to plasma membrane disruption through lipid peroxidation and has several other deleterious effects. A large body of literature suggests the involvement of ROS in cancer, ageing, and several other health hazards of the modern world. Plant-based cures for these conditions are desperately sought after as supposedly safer alternatives to mainstream medicines. Phytochemicals, which constitute a diverse group of plant-based substances with varying roles in oxidative reactions of the body, are implicated in the treatment of cancer, aging, and all other ROS-induced anomalies. This review presents a summary of important phytochemicals extracted from medicinal plants which are a part of Indian ethnomedicine and Ayurveda and describes their possible therapeutic significance.https://www.mdpi.com/2076-3921/10/10/1606ethnomedicineoxidative stressROScancerphytochemicals |
| spellingShingle | Nishat Fatima Syed Shabihe Raza Baqri Ahmad Alsulimani Sharmila Fagoonee Petr Slama Kavindra Kumar Kesari Shubhadeep Roychoudhury Shafiul Haque Phytochemicals from Indian Ethnomedicines: Promising Prospects for the Management of Oxidative Stress and Cancer Antioxidants ethnomedicine oxidative stress ROS cancer phytochemicals |
| title | Phytochemicals from Indian Ethnomedicines: Promising Prospects for the Management of Oxidative Stress and Cancer |
| title_full | Phytochemicals from Indian Ethnomedicines: Promising Prospects for the Management of Oxidative Stress and Cancer |
| title_fullStr | Phytochemicals from Indian Ethnomedicines: Promising Prospects for the Management of Oxidative Stress and Cancer |
| title_full_unstemmed | Phytochemicals from Indian Ethnomedicines: Promising Prospects for the Management of Oxidative Stress and Cancer |
| title_short | Phytochemicals from Indian Ethnomedicines: Promising Prospects for the Management of Oxidative Stress and Cancer |
| title_sort | phytochemicals from indian ethnomedicines promising prospects for the management of oxidative stress and cancer |
| topic | ethnomedicine oxidative stress ROS cancer phytochemicals |
| url | https://www.mdpi.com/2076-3921/10/10/1606 |
| work_keys_str_mv | AT nishatfatima phytochemicalsfromindianethnomedicinespromisingprospectsforthemanagementofoxidativestressandcancer AT syedshabiherazabaqri phytochemicalsfromindianethnomedicinespromisingprospectsforthemanagementofoxidativestressandcancer AT ahmadalsulimani phytochemicalsfromindianethnomedicinespromisingprospectsforthemanagementofoxidativestressandcancer AT sharmilafagoonee phytochemicalsfromindianethnomedicinespromisingprospectsforthemanagementofoxidativestressandcancer AT petrslama phytochemicalsfromindianethnomedicinespromisingprospectsforthemanagementofoxidativestressandcancer AT kavindrakumarkesari phytochemicalsfromindianethnomedicinespromisingprospectsforthemanagementofoxidativestressandcancer AT shubhadeeproychoudhury phytochemicalsfromindianethnomedicinespromisingprospectsforthemanagementofoxidativestressandcancer AT shafiulhaque phytochemicalsfromindianethnomedicinespromisingprospectsforthemanagementofoxidativestressandcancer |