Generation of iPSC lines from a Nijmegen Breakage Syndrome patient

Generation of iPSC lines from a Nijmegen Breakage Syndrome patient

Human dermal fibroblasts from a Nijmegen Breakage Syndrome (NBS) patient bearing the 657del5 mutation within the DNA repair gene NIBRIN were used to generate two iPSC-lines (vNBS8-iPS-c1, vNBS8-iPS-c2) by retroviral transduction of OCT4, SOX2, c-MYC and KLF4. Pluripotency was confirmed both in vivo...

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Bibliographic Details
Main Authors:	Barbara Mlody, James Adjaye
Format:	Article
Language:	English
Published:	Elsevier 2015-11-01
Series:	Stem Cell Research
Online Access:	http://www.sciencedirect.com/science/article/pii/S1873506115001488

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