Tripartite motif containing 62 is a novel prognostic marker and suppresses tumor metastasis via c-Jun/Slug signaling-mediated epithelial-mesenchymal transition in cervical cancer

Tripartite motif containing 62 is a novel prognostic marker and suppresses tumor metastasis via c-Jun/Slug signaling-mediated epithelial-mesenchymal transition in cervical cancer

Abstract Background TRIM62 (tripartite motif containing 62) has been found to act as a tumor suppressor of several cancers. However, its precise biological role and related mechanism remain unknown in cervical cancer (CC). Methods Quantitative Real-time PCR and western blot were adopted to detect th...

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Bibliographic Details
Main Authors: Tian-Yu Liu, Jian Chen, Chun-Liang Shang, Hong-Wei Shen, Jia-Ming Huang, Yan-Chun Liang, Wei Wang, Yun-He Zhao, Duo Liu, Man Shu, Lu-Yan Guo, Zheng Hu, Shu-Zhong Yao
Format: Article
Language:English
Published: BMC 2016-10-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Prognosis
Metastasis
EMT
MAPK
Slug
Online Access:http://link.springer.com/article/10.1186/s13046-016-0445-5

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