Cardiovascular Biomarkers: Lessons of the Past and Prospects for the Future
Cardiovascular diseases (CVDs) are a major healthcare burden on the population worldwide. Early detection of this disease is important in prevention and treatment to minimise morbidity and mortality. Biomarkers are a critical tool to either diagnose, screen, or provide prognostic information for pat...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-05-01
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| Series: | International Journal of Molecular Sciences |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1422-0067/23/10/5680 |
| _version_ | 1797499176107376640 |
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| author | Farah Omran Ioannis Kyrou Faizel Osman Ven Gee Lim Harpal Singh Randeva Kamaljit Chatha |
| author_facet | Farah Omran Ioannis Kyrou Faizel Osman Ven Gee Lim Harpal Singh Randeva Kamaljit Chatha |
| author_sort | Farah Omran |
| collection | DOAJ |
| description | Cardiovascular diseases (CVDs) are a major healthcare burden on the population worldwide. Early detection of this disease is important in prevention and treatment to minimise morbidity and mortality. Biomarkers are a critical tool to either diagnose, screen, or provide prognostic information for pathological conditions. This review discusses the historical cardiac biomarkers used to detect these conditions, discussing their application and their limitations. Identification of new biomarkers have since replaced these and are now in use in routine clinical practice, but still do not detect all disease. Future cardiac biomarkers are showing promise in early studies, but further studies are required to show their value in improving detection of CVD above the current biomarkers. Additionally, the analytical platforms that would allow them to be adopted in healthcare are yet to be established. There is also the need to identify whether these biomarkers can be used for diagnostic, prognostic, or screening purposes, which will impact their implementation in routine clinical practice. |
| first_indexed | 2024-03-10T03:43:41Z |
| format | Article |
| id | doaj.art-aa912e4f79e84c23b05268b0044b2905 |
| institution | Directory Open Access Journal |
| issn | 1661-6596 1422-0067 |
| language | English |
| last_indexed | 2024-03-10T03:43:41Z |
| publishDate | 2022-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | International Journal of Molecular Sciences |
| spelling | doaj.art-aa912e4f79e84c23b05268b0044b29052023-11-23T11:26:44ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672022-05-012310568010.3390/ijms23105680Cardiovascular Biomarkers: Lessons of the Past and Prospects for the FutureFarah Omran0Ioannis Kyrou1Faizel Osman2Ven Gee Lim3Harpal Singh Randeva4Kamaljit Chatha5Warwick Medical School, University of Warwick, Coventry CV4 7AL, UKWarwick Medical School, University of Warwick, Coventry CV4 7AL, UKWarwick Medical School, University of Warwick, Coventry CV4 7AL, UKWarwick Medical School, University of Warwick, Coventry CV4 7AL, UKWarwick Medical School, University of Warwick, Coventry CV4 7AL, UKWarwick Medical School, University of Warwick, Coventry CV4 7AL, UKCardiovascular diseases (CVDs) are a major healthcare burden on the population worldwide. Early detection of this disease is important in prevention and treatment to minimise morbidity and mortality. Biomarkers are a critical tool to either diagnose, screen, or provide prognostic information for pathological conditions. This review discusses the historical cardiac biomarkers used to detect these conditions, discussing their application and their limitations. Identification of new biomarkers have since replaced these and are now in use in routine clinical practice, but still do not detect all disease. Future cardiac biomarkers are showing promise in early studies, but further studies are required to show their value in improving detection of CVD above the current biomarkers. Additionally, the analytical platforms that would allow them to be adopted in healthcare are yet to be established. There is also the need to identify whether these biomarkers can be used for diagnostic, prognostic, or screening purposes, which will impact their implementation in routine clinical practice.https://www.mdpi.com/1422-0067/23/10/5680cardiovascular diseasesbiomarkersfuture biomarkers |
| spellingShingle | Farah Omran Ioannis Kyrou Faizel Osman Ven Gee Lim Harpal Singh Randeva Kamaljit Chatha Cardiovascular Biomarkers: Lessons of the Past and Prospects for the Future International Journal of Molecular Sciences cardiovascular diseases biomarkers future biomarkers |
| title | Cardiovascular Biomarkers: Lessons of the Past and Prospects for the Future |
| title_full | Cardiovascular Biomarkers: Lessons of the Past and Prospects for the Future |
| title_fullStr | Cardiovascular Biomarkers: Lessons of the Past and Prospects for the Future |
| title_full_unstemmed | Cardiovascular Biomarkers: Lessons of the Past and Prospects for the Future |
| title_short | Cardiovascular Biomarkers: Lessons of the Past and Prospects for the Future |
| title_sort | cardiovascular biomarkers lessons of the past and prospects for the future |
| topic | cardiovascular diseases biomarkers future biomarkers |
| url | https://www.mdpi.com/1422-0067/23/10/5680 |
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