Fetal lesions of EHV-1 in equine
Abstract EHV-1 infection is responsible for huge economic losses in equines due to abortion and neonatal mortality. In this study, we describe 4 cases of abortion and neonatal deaths from pregnant mares and a she-donkey from different localities in Egypt during the period from May 2015 to October 20...
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| Format: | Article |
| Language: | English |
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Academia Brasileira de Ciências
2020-09-01
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| Series: | Anais da Academia Brasileira de Ciências |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652020000400715&tlng=en |
| _version_ | 1798015122135842816 |
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| author | ABDELMONEIM A. ALI NAHLA A. REFAT NAIF A. ALGABRI MOHAMMED S. SOBH |
| author_facet | ABDELMONEIM A. ALI NAHLA A. REFAT NAIF A. ALGABRI MOHAMMED S. SOBH |
| author_sort | ABDELMONEIM A. ALI |
| collection | DOAJ |
| description | Abstract EHV-1 infection is responsible for huge economic losses in equines due to abortion and neonatal mortality. In this study, we describe 4 cases of abortion and neonatal deaths from pregnant mares and a she-donkey from different localities in Egypt during the period from May 2015 to October 2017. Attempts were made to isolate and identify EHV-1, in addition to compare the different pathological lesions in various tissues of the necropsied cases. EHV-1 was successfully isolated from two aborted fetuses and one dead neonatal foal from mares, beside one aborted fetus from a she-donkey. The positive cases showed cytopathic effect on embryonated chicken eggs scattered on chorioallantoic membrane. Moreover, PCR was applied for the pock lesions and revealed positive results for EHV-1. Interstitial pneumonia, bronchopneumonia and necrosis of hepatic, myocardial, microcotyledonary tissues besides disseminated thrombi were the main encountered lesions. Intranuclear inclusion bodies were demonstrated in brain, liver, placenta and pulmonary tissues. Here, we describe EHV-1 induced brain lesions represented by degenerated neurons, vascular endotheliosis with intranuclear inclusion bodies in the aborted she-donkey fetus. Lesions were more sever in the aborted fetuses from mares than the one from the she-donkey. EHV-1 antigen was detected by immunohistochemistry staining. |
| first_indexed | 2024-04-11T15:29:29Z |
| format | Article |
| id | doaj.art-aa91d518549c471790348522d13f864c |
| institution | Directory Open Access Journal |
| issn | 1678-2690 |
| language | English |
| last_indexed | 2024-04-11T15:29:29Z |
| publishDate | 2020-09-01 |
| publisher | Academia Brasileira de Ciências |
| record_format | Article |
| series | Anais da Academia Brasileira de Ciências |
| spelling | doaj.art-aa91d518549c471790348522d13f864c2022-12-22T04:16:11ZengAcademia Brasileira de CiênciasAnais da Academia Brasileira de Ciências1678-26902020-09-0192suppl 210.1590/0001-3765202020180837Fetal lesions of EHV-1 in equineABDELMONEIM A. ALIhttps://orcid.org/0000-0003-4824-5624NAHLA A. REFAThttps://orcid.org/0000-0001-5702-1329NAIF A. ALGABRIhttps://orcid.org/0000-0002-5679-2532MOHAMMED S. SOBHhttps://orcid.org/0000-0002-6547-1255Abstract EHV-1 infection is responsible for huge economic losses in equines due to abortion and neonatal mortality. In this study, we describe 4 cases of abortion and neonatal deaths from pregnant mares and a she-donkey from different localities in Egypt during the period from May 2015 to October 2017. Attempts were made to isolate and identify EHV-1, in addition to compare the different pathological lesions in various tissues of the necropsied cases. EHV-1 was successfully isolated from two aborted fetuses and one dead neonatal foal from mares, beside one aborted fetus from a she-donkey. The positive cases showed cytopathic effect on embryonated chicken eggs scattered on chorioallantoic membrane. Moreover, PCR was applied for the pock lesions and revealed positive results for EHV-1. Interstitial pneumonia, bronchopneumonia and necrosis of hepatic, myocardial, microcotyledonary tissues besides disseminated thrombi were the main encountered lesions. Intranuclear inclusion bodies were demonstrated in brain, liver, placenta and pulmonary tissues. Here, we describe EHV-1 induced brain lesions represented by degenerated neurons, vascular endotheliosis with intranuclear inclusion bodies in the aborted she-donkey fetus. Lesions were more sever in the aborted fetuses from mares than the one from the she-donkey. EHV-1 antigen was detected by immunohistochemistry staining.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652020000400715&tlng=enabortionEHVsfetusneonatalmaresshe-donkey |
| spellingShingle | ABDELMONEIM A. ALI NAHLA A. REFAT NAIF A. ALGABRI MOHAMMED S. SOBH Fetal lesions of EHV-1 in equine Anais da Academia Brasileira de Ciências abortion EHVs fetus neonatal mares she-donkey |
| title | Fetal lesions of EHV-1 in equine |
| title_full | Fetal lesions of EHV-1 in equine |
| title_fullStr | Fetal lesions of EHV-1 in equine |
| title_full_unstemmed | Fetal lesions of EHV-1 in equine |
| title_short | Fetal lesions of EHV-1 in equine |
| title_sort | fetal lesions of ehv 1 in equine |
| topic | abortion EHVs fetus neonatal mares she-donkey |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652020000400715&tlng=en |
| work_keys_str_mv | AT abdelmoneimaali fetallesionsofehv1inequine AT nahlaarefat fetallesionsofehv1inequine AT naifaalgabri fetallesionsofehv1inequine AT mohammedssobh fetallesionsofehv1inequine |