A novel specific aptamer targets cerebrovascular endothelial cells after ischemic stroke
Abstract Cell specific-targeted therapy (CSTT) for acute ischemic stroke remains underdeveloped. Cerebrovascular endothelial cells (CECs) are key components of the blood–brain barrier and are the first brain cells affected by ischemic stroke. After stroke, CEC injury causes insufficient energy suppl...
Main Authors: | Heng Hu, Silin Wu, Tae Jin Lee, Aaron M. Gusdon, Yuxin Liu, Huimahn A. Choi, Xuefang Sophie Ren |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-06-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-023-36993-6 |
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