Mirogabalin - the use of a new gabapentinoid in the treatment of diabetic neuropathy and postherpetic neuropathy and other conditions

Introduction: Mirogabalin is a new drug from the gabapentinoid group first registered in Japan in 2019. It has found use in the treatment of peripheral neuropathic pain in diabetic neuropathy and postherpetic neuropathy. Purpose: In this article, we review studies on the efficacy and safety of mi...

Full description

Bibliographic Details
Main Authors: Weronika Gawel, Sylwia Zdun, Klaudia Walczak, Zuzanna Wesołowska, Przemysław Jędruszczak
Format: Article
Language:English
Published: Nicolaus Copernicus University in Toruń 2023-01-01
Series:Quality in Sport
Subjects:
Online Access:https://apcz.umk.pl/QS/article/view/41950
_version_ 1811176035614457856
author Weronika Gawel
Sylwia Zdun
Klaudia Walczak
Zuzanna Wesołowska
Przemysław Jędruszczak
author_facet Weronika Gawel
Sylwia Zdun
Klaudia Walczak
Zuzanna Wesołowska
Przemysław Jędruszczak
author_sort Weronika Gawel
collection DOAJ
description Introduction: Mirogabalin is a new drug from the gabapentinoid group first registered in Japan in 2019. It has found use in the treatment of peripheral neuropathic pain in diabetic neuropathy and postherpetic neuropathy. Purpose: In this article, we review studies on the efficacy and safety of mirogabalin in the treatment of registered indications and its potentially new applications. Materials and Methods: We reviewed the literature available in the PubMed database, using the key words: "mirogabalin", "neuropathy" "pregabalin". Results: Mirogabalin has been registered for the treatment of neuropathic pain in diabetic neuropathy and postherpetic neuropathy. The literature shows that it is effective and safe in the above-mentioned indications.  Its use has also been described: in the treatment of neuropathic pain of other etiologies with intolerance to pregabalin, as a coanalgesic in the treatment of pain in the course of cancer, and in neuropathy caused by chemotherapy. It has been shown to be effective in all of the aforementioned cases. Studies have shown no clinically significant effect of mirogabalin in the symptomatic treatment of fibromyalgia pain.  It has a good safety profile and a low number of adverse effects. Conclusions:. Mirogabalin is a drug that has the potential to improve the efficacy of treatment of neuropathic pain due to various causes.  There is a need to continue conducting studies on larger groups of patients in order to make wider use of its potential in clinical practice.
first_indexed 2024-04-10T19:46:34Z
format Article
id doaj.art-aa99b93633a747db8b8777a35a274158
institution Directory Open Access Journal
issn 2450-3118
language English
last_indexed 2024-04-10T19:46:34Z
publishDate 2023-01-01
publisher Nicolaus Copernicus University in Toruń
record_format Article
series Quality in Sport
spelling doaj.art-aa99b93633a747db8b8777a35a2741582023-01-29T11:51:35ZengNicolaus Copernicus University in ToruńQuality in Sport2450-31182023-01-019110.12775/QS.2023.09.01.007Mirogabalin - the use of a new gabapentinoid in the treatment of diabetic neuropathy and postherpetic neuropathy and other conditionsWeronika Gawel0Sylwia Zdun1Klaudia Walczak2Zuzanna Wesołowska3Przemysław Jędruszczak4Absolwent Uniwersytetu Medycznego w LublinieAbsolwent Uniwersytetu Medycznego w LublinieAbsolwent Uniwersytetu Medycznego w LublinieAbsolwent Uniwersytetu Medycznego w LublinieAbsolwent Uniwersytetu Medycznego w Lublinie Introduction: Mirogabalin is a new drug from the gabapentinoid group first registered in Japan in 2019. It has found use in the treatment of peripheral neuropathic pain in diabetic neuropathy and postherpetic neuropathy. Purpose: In this article, we review studies on the efficacy and safety of mirogabalin in the treatment of registered indications and its potentially new applications. Materials and Methods: We reviewed the literature available in the PubMed database, using the key words: "mirogabalin", "neuropathy" "pregabalin". Results: Mirogabalin has been registered for the treatment of neuropathic pain in diabetic neuropathy and postherpetic neuropathy. The literature shows that it is effective and safe in the above-mentioned indications.  Its use has also been described: in the treatment of neuropathic pain of other etiologies with intolerance to pregabalin, as a coanalgesic in the treatment of pain in the course of cancer, and in neuropathy caused by chemotherapy. It has been shown to be effective in all of the aforementioned cases. Studies have shown no clinically significant effect of mirogabalin in the symptomatic treatment of fibromyalgia pain.  It has a good safety profile and a low number of adverse effects. Conclusions:. Mirogabalin is a drug that has the potential to improve the efficacy of treatment of neuropathic pain due to various causes.  There is a need to continue conducting studies on larger groups of patients in order to make wider use of its potential in clinical practice. https://apcz.umk.pl/QS/article/view/41950mirogabalinneuropathypregabalin
spellingShingle Weronika Gawel
Sylwia Zdun
Klaudia Walczak
Zuzanna Wesołowska
Przemysław Jędruszczak
Mirogabalin - the use of a new gabapentinoid in the treatment of diabetic neuropathy and postherpetic neuropathy and other conditions
Quality in Sport
mirogabalin
neuropathy
pregabalin
title Mirogabalin - the use of a new gabapentinoid in the treatment of diabetic neuropathy and postherpetic neuropathy and other conditions
title_full Mirogabalin - the use of a new gabapentinoid in the treatment of diabetic neuropathy and postherpetic neuropathy and other conditions
title_fullStr Mirogabalin - the use of a new gabapentinoid in the treatment of diabetic neuropathy and postherpetic neuropathy and other conditions
title_full_unstemmed Mirogabalin - the use of a new gabapentinoid in the treatment of diabetic neuropathy and postherpetic neuropathy and other conditions
title_short Mirogabalin - the use of a new gabapentinoid in the treatment of diabetic neuropathy and postherpetic neuropathy and other conditions
title_sort mirogabalin the use of a new gabapentinoid in the treatment of diabetic neuropathy and postherpetic neuropathy and other conditions
topic mirogabalin
neuropathy
pregabalin
url https://apcz.umk.pl/QS/article/view/41950
work_keys_str_mv AT weronikagawel mirogabalintheuseofanewgabapentinoidinthetreatmentofdiabeticneuropathyandpostherpeticneuropathyandotherconditions
AT sylwiazdun mirogabalintheuseofanewgabapentinoidinthetreatmentofdiabeticneuropathyandpostherpeticneuropathyandotherconditions
AT klaudiawalczak mirogabalintheuseofanewgabapentinoidinthetreatmentofdiabeticneuropathyandpostherpeticneuropathyandotherconditions
AT zuzannawesołowska mirogabalintheuseofanewgabapentinoidinthetreatmentofdiabeticneuropathyandpostherpeticneuropathyandotherconditions
AT przemysławjedruszczak mirogabalintheuseofanewgabapentinoidinthetreatmentofdiabeticneuropathyandpostherpeticneuropathyandotherconditions