PSYCHOTIC DISORDERS IN PEOPLE USING SYNTHETIC CANNABINOIDS (SPICE)
The study involved the group of patients (n = 40) with psychotic disorders who used synthetic cannabinoids (spice). Among the psychotic disorders according to ICD-10 we allocated intoxication delirium (F12.03; 35 %), schizophreniform disorder (F12.50; 60 %), disorder with predominantly manic psychot...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
Scientific Сentre for Family Health and Human Reproduction Problems
2017-04-01
|
| Series: | Acta Biomedica Scientifica |
| Subjects: | |
| Online Access: | https://www.actabiomedica.ru/jour/article/view/610 |
| _version_ | 1826853412034052096 |
|---|---|
| author | L. A. Ivanova T. V. Terskikh T. V. Tarasenko L. V. Ivanova |
| author_facet | L. A. Ivanova T. V. Terskikh T. V. Tarasenko L. V. Ivanova |
| author_sort | L. A. Ivanova |
| collection | DOAJ |
| description | The study involved the group of patients (n = 40) with psychotic disorders who used synthetic cannabinoids (spice). Among the psychotic disorders according to ICD-10 we allocated intoxication delirium (F12.03; 35 %), schizophreniform disorder (F12.50; 60 %), disorder with predominantly manic psychotic symptoms (F12.55; 5 %). The average age of patients was 25.2 ± 4.4 years. Hereditary aggravation in patients who consume synthetic cannabinoids was presented by alcoholism and substance abuse (20 %), affective disorders (7.5 %), schizophrenia (5 %); personality disorders (10 %); suicides (2.5 %). The group of patients with intoxication with delirium had significantly higher frequency of family history of alcoholism and addiction to psychoactive substances compared with patients with schizophreniform disorder (p < 0.02). Clinic intoxication delirium was characterized by disturbance of consciousness (delirium, twilight) lasting from several hours to 2-3 days, psychomotor agitation, aggression, shouting certain phrases and words, anxiety, fear, visual hallucinations. In patients with acute schizophreniform disorder (24 patients; 60 %) symptoms consisted of a dominant affect (depressive, or mixed), productive psychopathological symptoms within the list of F20 headings of ICD-10. Productive syndromes were limited to verbal hallucinosis (true or its limiting variants) in the form of voiced (which discuss the patient's behavior, threaten him/her with death, offer advice), reference of persecutory delusion. The coming out of a psychotic state was characterized by short-term postpsychotic depression. Patients received detoxification therapy and also combined psychopharmacotherapy with the use of antipsychotics, antidepressants, tranquilizers, normotymics, nootropics. |
| first_indexed | 2024-03-08T12:18:12Z |
| format | Article |
| id | doaj.art-aa9b126a2898407c98d0c842d2ba8b4f |
| institution | Directory Open Access Journal |
| issn | 2541-9420 2587-9596 |
| language | Russian |
| last_indexed | 2025-02-16T17:25:03Z |
| publishDate | 2017-04-01 |
| publisher | Scientific Сentre for Family Health and Human Reproduction Problems |
| record_format | Article |
| series | Acta Biomedica Scientifica |
| spelling | doaj.art-aa9b126a2898407c98d0c842d2ba8b4f2025-01-27T16:48:51ZrusScientific Сentre for Family Health and Human Reproduction ProblemsActa Biomedica Scientifica2541-94202587-95962017-04-0122141710.12737/article_59a614f6883957.55938557610PSYCHOTIC DISORDERS IN PEOPLE USING SYNTHETIC CANNABINOIDS (SPICE)L. A. Ivanova0T. V. Terskikh1T. V. Tarasenko2L. V. Ivanova3Irkutsk State Medical Academy of Postgraduate Education - Branch Campus of the Russian Medical Academy of Continuing Professional EducationIrkutsk Regional Psychoneurologic DispensaryIrkutsk Regional Psychoneurologic DispensaryIrkutsk State Medical Academy of Postgraduate Education - Branch Campus of the Russian Medical Academy of Continuing Professional EducationThe study involved the group of patients (n = 40) with psychotic disorders who used synthetic cannabinoids (spice). Among the psychotic disorders according to ICD-10 we allocated intoxication delirium (F12.03; 35 %), schizophreniform disorder (F12.50; 60 %), disorder with predominantly manic psychotic symptoms (F12.55; 5 %). The average age of patients was 25.2 ± 4.4 years. Hereditary aggravation in patients who consume synthetic cannabinoids was presented by alcoholism and substance abuse (20 %), affective disorders (7.5 %), schizophrenia (5 %); personality disorders (10 %); suicides (2.5 %). The group of patients with intoxication with delirium had significantly higher frequency of family history of alcoholism and addiction to psychoactive substances compared with patients with schizophreniform disorder (p < 0.02). Clinic intoxication delirium was characterized by disturbance of consciousness (delirium, twilight) lasting from several hours to 2-3 days, psychomotor agitation, aggression, shouting certain phrases and words, anxiety, fear, visual hallucinations. In patients with acute schizophreniform disorder (24 patients; 60 %) symptoms consisted of a dominant affect (depressive, or mixed), productive psychopathological symptoms within the list of F20 headings of ICD-10. Productive syndromes were limited to verbal hallucinosis (true or its limiting variants) in the form of voiced (which discuss the patient's behavior, threaten him/her with death, offer advice), reference of persecutory delusion. The coming out of a psychotic state was characterized by short-term postpsychotic depression. Patients received detoxification therapy and also combined psychopharmacotherapy with the use of antipsychotics, antidepressants, tranquilizers, normotymics, nootropics.https://www.actabiomedica.ru/jour/article/view/610acute psychosissynthetic cannabinoids (spice) |
| spellingShingle | L. A. Ivanova T. V. Terskikh T. V. Tarasenko L. V. Ivanova PSYCHOTIC DISORDERS IN PEOPLE USING SYNTHETIC CANNABINOIDS (SPICE) Acta Biomedica Scientifica acute psychosis synthetic cannabinoids (spice) |
| title | PSYCHOTIC DISORDERS IN PEOPLE USING SYNTHETIC CANNABINOIDS (SPICE) |
| title_full | PSYCHOTIC DISORDERS IN PEOPLE USING SYNTHETIC CANNABINOIDS (SPICE) |
| title_fullStr | PSYCHOTIC DISORDERS IN PEOPLE USING SYNTHETIC CANNABINOIDS (SPICE) |
| title_full_unstemmed | PSYCHOTIC DISORDERS IN PEOPLE USING SYNTHETIC CANNABINOIDS (SPICE) |
| title_short | PSYCHOTIC DISORDERS IN PEOPLE USING SYNTHETIC CANNABINOIDS (SPICE) |
| title_sort | psychotic disorders in people using synthetic cannabinoids spice |
| topic | acute psychosis synthetic cannabinoids (spice) |
| url | https://www.actabiomedica.ru/jour/article/view/610 |
| work_keys_str_mv | AT laivanova psychoticdisordersinpeopleusingsyntheticcannabinoidsspice AT tvterskikh psychoticdisordersinpeopleusingsyntheticcannabinoidsspice AT tvtarasenko psychoticdisordersinpeopleusingsyntheticcannabinoidsspice AT lvivanova psychoticdisordersinpeopleusingsyntheticcannabinoidsspice |