Modafinil. Armodafinil. The use of eugeroics in assisting the treatment of depression, bipolar disorder, and schizophrenia. Benefits, drawbacks, and adverse effects

Modafinil is used to treat narcolepsy with cataplexy and is also being extensively studied to find new therapeutic uses. In recent years, there have been reports suggesting the potential benefits of modafinil in the treatment of psychiatric illnesses such as depression and bipolar depression. In th...

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Main Authors: Norbert Kandefer, Anna Jaremek, Joanna Kępa, Michał Wyszkowski, Aleksandra Grabarczyk, Anna Pawlak, Sylwia Grad, Paweł Gregorek, Małgorzata Gregorek, Laura Loryś, Klaudia Klimczak
Format: Article
Language:English
Published: Kazimierz Wielki University 2023-08-01
Series:Journal of Education, Health and Sport
Subjects:
Online Access:https://apcz.umk.pl/JEHS/article/view/45110
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author Norbert Kandefer
Anna Jaremek
Joanna Kępa
Michał Wyszkowski
Aleksandra Grabarczyk
Anna Pawlak
Sylwia Grad
Paweł Gregorek
Małgorzata Gregorek
Laura Loryś
Klaudia Klimczak
author_facet Norbert Kandefer
Anna Jaremek
Joanna Kępa
Michał Wyszkowski
Aleksandra Grabarczyk
Anna Pawlak
Sylwia Grad
Paweł Gregorek
Małgorzata Gregorek
Laura Loryś
Klaudia Klimczak
author_sort Norbert Kandefer
collection DOAJ
description Modafinil is used to treat narcolepsy with cataplexy and is also being extensively studied to find new therapeutic uses. In recent years, there have been reports suggesting the potential benefits of modafinil in the treatment of psychiatric illnesses such as depression and bipolar depression. In the case of depression, modafinil can be used as an adjuvant or as monotherapy in patients who do not respond sufficiently to antidepressants. Studies have shown that modafinil improves symptoms of depression, reduces fatigue and improves cognitive function. There are also reports of a beneficial effect of modafinil in the treatment of seasonal depression. For bipolar depression, modafinil can be used as an adjunct therapy during the depressive phase, particularly in patients experiencing slowness, lethargy and loss of pleasure. Studies suggest that modafinil may improve depressive symptoms without inducing manic episodes. There are also data indicating modafinil's potential efficacy in treating negative symptoms and improving cognitive function in patients with schizophrenia. In conclusion, modafinil appears to be a promising drug in aiding the treatment of various psychiatric illnesses.
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spelling doaj.art-aa9cf0e5b53740ef99540abcb6f9bcea2023-08-19T10:48:27ZengKazimierz Wielki UniversityJournal of Education, Health and Sport2391-83062023-08-0143110.12775/JEHS.2023.43.01.020Modafinil. Armodafinil. The use of eugeroics in assisting the treatment of depression, bipolar disorder, and schizophrenia. Benefits, drawbacks, and adverse effectsNorbert Kandefer0Anna Jaremek1Joanna Kępa2Michał Wyszkowski3Aleksandra Grabarczyk4Anna Pawlak5Sylwia Grad6Paweł Gregorek7Małgorzata Gregorek8Laura Loryś9Klaudia Klimczak10Uniwersytet Medyczny w LublinieIndependent Public Clinical Hospital No. 4 in Lublin, 8 Doktora Kazimierza Jaczewskiego Street, 20-954 LublinIndependent Public Clinical Hospital No. 4 in Lublin, 8 Doktora Kazimierza Jaczewskiego Street, 20-954 Lublin.Independent Public Clinical Hospital No. 4 in Lublin, 8 Doktora Kazimierza Jaczewskiego Street, 20-954 Lublin.Steafan Kardynał Wyszyński Province Specialist Hospital in Lublin, 100 Aleja Kraśnicka, 20-718 Lublin. Independent Public Clinical Hospital No. 4 in Lublin, 8 Doktora Kazimierza Jaczewskiego Street, 20-954 Lublin.Independent Public Clinical Hospital No. 4 in Lublin, 8 Doktora Kazimierza Jaczewskiego Street, 20-954 Lublin.Independent Public Clinical Hospital No. 4 in Lublin, 8 Doktora Kazimierza Jaczewskiego Street, 20-954 Lublin.Independent Public Clinical Hospital No. 4 in Lublin, 8 Doktora Kazimierza Jaczewskiego Street, 20-954 Lublin.Medical University of Lublin, 1 Al. Racławickie, 20-059 Lublin.Medical University of Lublin, 1 Al. Racławickie, 20-059 Lublin. Modafinil is used to treat narcolepsy with cataplexy and is also being extensively studied to find new therapeutic uses. In recent years, there have been reports suggesting the potential benefits of modafinil in the treatment of psychiatric illnesses such as depression and bipolar depression. In the case of depression, modafinil can be used as an adjuvant or as monotherapy in patients who do not respond sufficiently to antidepressants. Studies have shown that modafinil improves symptoms of depression, reduces fatigue and improves cognitive function. There are also reports of a beneficial effect of modafinil in the treatment of seasonal depression. For bipolar depression, modafinil can be used as an adjunct therapy during the depressive phase, particularly in patients experiencing slowness, lethargy and loss of pleasure. Studies suggest that modafinil may improve depressive symptoms without inducing manic episodes. There are also data indicating modafinil's potential efficacy in treating negative symptoms and improving cognitive function in patients with schizophrenia. In conclusion, modafinil appears to be a promising drug in aiding the treatment of various psychiatric illnesses. https://apcz.umk.pl/JEHS/article/view/45110ModafinilPsychiatricDepressionBipolarSchizophrenia
spellingShingle Norbert Kandefer
Anna Jaremek
Joanna Kępa
Michał Wyszkowski
Aleksandra Grabarczyk
Anna Pawlak
Sylwia Grad
Paweł Gregorek
Małgorzata Gregorek
Laura Loryś
Klaudia Klimczak
Modafinil. Armodafinil. The use of eugeroics in assisting the treatment of depression, bipolar disorder, and schizophrenia. Benefits, drawbacks, and adverse effects
Journal of Education, Health and Sport
Modafinil
Psychiatric
Depression
Bipolar
Schizophrenia
title Modafinil. Armodafinil. The use of eugeroics in assisting the treatment of depression, bipolar disorder, and schizophrenia. Benefits, drawbacks, and adverse effects
title_full Modafinil. Armodafinil. The use of eugeroics in assisting the treatment of depression, bipolar disorder, and schizophrenia. Benefits, drawbacks, and adverse effects
title_fullStr Modafinil. Armodafinil. The use of eugeroics in assisting the treatment of depression, bipolar disorder, and schizophrenia. Benefits, drawbacks, and adverse effects
title_full_unstemmed Modafinil. Armodafinil. The use of eugeroics in assisting the treatment of depression, bipolar disorder, and schizophrenia. Benefits, drawbacks, and adverse effects
title_short Modafinil. Armodafinil. The use of eugeroics in assisting the treatment of depression, bipolar disorder, and schizophrenia. Benefits, drawbacks, and adverse effects
title_sort modafinil armodafinil the use of eugeroics in assisting the treatment of depression bipolar disorder and schizophrenia benefits drawbacks and adverse effects
topic Modafinil
Psychiatric
Depression
Bipolar
Schizophrenia
url https://apcz.umk.pl/JEHS/article/view/45110
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