Activation and substrate specificity of the human P4-ATPase ATP8B1

Activation and substrate specificity of the human P4-ATPase ATP8B1

Abstract Asymmetric distribution of phospholipids in eukaryotic membranes is essential for cell integrity, signaling pathways, and vesicular trafficking. P4-ATPases, also known as flippases, participate in creating and maintaining this asymmetry through active transport of phospholipids from the exo...

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Bibliographic Details
Main Authors:	Thibaud Dieudonné, Felix Kümmerer, Michelle Juknaviciute Laursen, Charlott Stock, Rasmus Kock Flygaard, Syma Khalid, Guillaume Lenoir, Joseph A. Lyons, Kresten Lindorff-Larsen, Poul Nissen
Format:	Article
Language:	English
Published:	Nature Portfolio 2023-11-01
Series:	Nature Communications
Online Access:	https://doi.org/10.1038/s41467-023-42828-9

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