Genetic variation of the Plasmodium falciparum circumsporozoite protein in parasite isolates from Homabay County in Kenya

Genetic variation of the Plasmodium falciparum circumsporozoite protein in parasite isolates from Homabay County in Kenya

The Plasmodium falciparum Circumsporozoite Protein (PfCSP) has been used in developing the RTS,S, and R21 malaria vaccines. However, genetic polymorphisms within Pfcsp compromise the effectiveness of the vaccine. Thus, it is essential to continuously assess the genetic diversity of Pfcsp, especially...

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Bibliographic Details
Main Authors:	Michael Maina, Sebastian Musundi, Josiah Kuja, Harrison Waweru, Daniel Kiboi, Bernard N. Kanoi, Jesse Gitaka
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-04-01
Series:	Frontiers in Parasitology
Subjects:	circumsporozoite protein vaccines genetic diversity Plasmodium falciparum malaria
Online Access:	https://www.frontiersin.org/articles/10.3389/fpara.2024.1346017/full

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