A Critical Review on Obstetric Follow-up ofWomen Affected by Systemic Lupus Erythematosus
Abstract Objective To review the existing recommendations on the prenatal care of women with systemic lupus erythematosus (SLE), based on currently available scientific evidence. Methods An integrative review was performed by two independent researchers, based on the literature available in the...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Federação Brasileira das Sociedades de Ginecologia e Obstetrícia
2018-04-01
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| Series: | Revista Brasileira de Ginecologia e Obstetrícia |
| Subjects: | |
| Online Access: | http://www.scielo.br/pdf/rbgo/v40n4/0100-7203-rbgo-40-04-00209.pdf |
| _version_ | 1819003448525324288 |
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| author | Danilo Eduardo Abib Pastore Maria Laura Costa Mary Angela Parpinelli Fernanda Garanhani Surita |
| author_facet | Danilo Eduardo Abib Pastore Maria Laura Costa Mary Angela Parpinelli Fernanda Garanhani Surita |
| author_sort | Danilo Eduardo Abib Pastore |
| collection | DOAJ |
| description | Abstract Objective To review the existing recommendations on the prenatal care of women with systemic lupus erythematosus (SLE), based on currently available scientific evidence. Methods An integrative review was performed by two independent researchers, based on the literature available in the MEDLINE (via PubMed), EMBASE and The Cochrane Library databases, using the medical subject headings (MeSH) terms “systemic lupus erythematosus” AND “high-risk pregnancy” OR “prenatal care.” Studies published in English between 2007 and 2017 were included; experimental studies and case reports were excluded. In cases of disagreement regarding the inclusion of studies, a third senior researcher was consulted. Forty titles were initially identified; four duplicates were excluded. After reading the abstracts, 7 were further excluded and 29 were selected for a full-text evaluation. Results Systemic lupus erythematosus flares, preeclampsia, gestation loss, preterm birth, fetal growth restriction and neonatal lupus syndromes (mainly congenital heartblock) were the major complications described. The multidisciplinary team should adopt a specific monitoring, with particular therapeutic protocols. There are safe and effective drug options that should be prescribed for a good control of SLE activity. Conclusion Pregnant women with SLE present an increased risk for maternal complications, pregnancy loss and other adverse outcomes. The disease activity may worsen and, thereby, increase the risk of other maternal-fetal complications. Thus, maintaining an adequate control of disease activity and treating flares quickly should be a central goal during prenatal care. |
| first_indexed | 2024-12-20T23:21:10Z |
| format | Article |
| id | doaj.art-aaa2b49ef40646309ebfc848c3453f1e |
| institution | Directory Open Access Journal |
| issn | 0100-7203 |
| language | English |
| last_indexed | 2024-12-20T23:21:10Z |
| publishDate | 2018-04-01 |
| publisher | Federação Brasileira das Sociedades de Ginecologia e Obstetrícia |
| record_format | Article |
| series | Revista Brasileira de Ginecologia e Obstetrícia |
| spelling | doaj.art-aaa2b49ef40646309ebfc848c3453f1e2022-12-21T19:23:31ZengFederação Brasileira das Sociedades de Ginecologia e ObstetríciaRevista Brasileira de Ginecologia e Obstetrícia0100-72032018-04-0140420922410.1055/s-0038-1625951A Critical Review on Obstetric Follow-up ofWomen Affected by Systemic Lupus ErythematosusDanilo Eduardo Abib PastoreMaria Laura CostaMary Angela ParpinelliFernanda Garanhani SuritaAbstract Objective To review the existing recommendations on the prenatal care of women with systemic lupus erythematosus (SLE), based on currently available scientific evidence. Methods An integrative review was performed by two independent researchers, based on the literature available in the MEDLINE (via PubMed), EMBASE and The Cochrane Library databases, using the medical subject headings (MeSH) terms “systemic lupus erythematosus” AND “high-risk pregnancy” OR “prenatal care.” Studies published in English between 2007 and 2017 were included; experimental studies and case reports were excluded. In cases of disagreement regarding the inclusion of studies, a third senior researcher was consulted. Forty titles were initially identified; four duplicates were excluded. After reading the abstracts, 7 were further excluded and 29 were selected for a full-text evaluation. Results Systemic lupus erythematosus flares, preeclampsia, gestation loss, preterm birth, fetal growth restriction and neonatal lupus syndromes (mainly congenital heartblock) were the major complications described. The multidisciplinary team should adopt a specific monitoring, with particular therapeutic protocols. There are safe and effective drug options that should be prescribed for a good control of SLE activity. Conclusion Pregnant women with SLE present an increased risk for maternal complications, pregnancy loss and other adverse outcomes. The disease activity may worsen and, thereby, increase the risk of other maternal-fetal complications. Thus, maintaining an adequate control of disease activity and treating flares quickly should be a central goal during prenatal care.http://www.scielo.br/pdf/rbgo/v40n4/0100-7203-rbgo-40-04-00209.pdfsystemic lupus erythematosuspregnancyprenatal carematernal outcomesfetal outcomes |
| spellingShingle | Danilo Eduardo Abib Pastore Maria Laura Costa Mary Angela Parpinelli Fernanda Garanhani Surita A Critical Review on Obstetric Follow-up ofWomen Affected by Systemic Lupus Erythematosus Revista Brasileira de Ginecologia e Obstetrícia systemic lupus erythematosus pregnancy prenatal care maternal outcomes fetal outcomes |
| title | A Critical Review on Obstetric Follow-up ofWomen Affected by Systemic Lupus Erythematosus |
| title_full | A Critical Review on Obstetric Follow-up ofWomen Affected by Systemic Lupus Erythematosus |
| title_fullStr | A Critical Review on Obstetric Follow-up ofWomen Affected by Systemic Lupus Erythematosus |
| title_full_unstemmed | A Critical Review on Obstetric Follow-up ofWomen Affected by Systemic Lupus Erythematosus |
| title_short | A Critical Review on Obstetric Follow-up ofWomen Affected by Systemic Lupus Erythematosus |
| title_sort | critical review on obstetric follow up ofwomen affected by systemic lupus erythematosus |
| topic | systemic lupus erythematosus pregnancy prenatal care maternal outcomes fetal outcomes |
| url | http://www.scielo.br/pdf/rbgo/v40n4/0100-7203-rbgo-40-04-00209.pdf |
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