Vasculitis as a Major Morbidity Factor in Patients With Partial RAG Deficiency

Vasculitis as a Major Morbidity Factor in Patients With Partial RAG Deficiency

Vasculitis can be a life-threatening complication associated with high mortality and morbidity among patients with primary immunodeficiencies (PIDs), including variants of severe and combined immunodeficiencies ((S)CID). Our understanding of vasculitis in partial defects in recombination activating...

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Main Authors: Christoph B. Geier, Jocelyn R. Farmer, Zsofia Foldvari, Boglarka Ujhazi, Jolanda Steininger, John W. Sleasman, Suhag Parikh, Meredith A. Dilley, Sung-Yun Pai, Lauren Henderson, Melissa Hazen, Benedicte Neven, Despina Moshous, Svetlana O. Sharapova, Snezhina Mihailova, Petya Yankova, Elisaveta Naumova, Seza Özen, Kevin Byram, James Fernandez, Hermann M. Wolf, Martha M. Eibl, Luigi D. Notarangelo, Leonard H. Calabrese, Jolan E. Walter
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Immunology
Subjects:
vasculitis
primary immumunodeficiencies
rag deficiency
severe combined immunodeficiencies (SCID)
autoimmunity
combined immunodeficiency with granuloma and/or autoimmunity
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.574738/full

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