Injection of hybrid 3D spheroids composed of podocytes, mesenchymal stem cells, and vascular endothelial cells into the renal cortex improves kidney function and replenishes glomerular podocytes

Injection of hybrid 3D spheroids composed of podocytes, mesenchymal stem cells, and vascular endothelial cells into the renal cortex improves kidney function and replenishes glomerular podocytes

Abstract Podocytes are highly differentiated epithelial cells that are crucial for maintaining the glomerular filtration barrier in the kidney. Podocyte injury followed by depletion is the major cause of pathological progression of kidney diseases. Although cell therapy has been considered a promisi...

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Bibliographic Details
Main Authors: Wen‐Yu Yang, Li‐Chi Chen, Ya‐Ting Jhuang, Yu‐Jie Lin, Pei‐Yu Hung, Yi‐Ching Ko, Meng‐Yu Tsai, Yun‐Wei Lee, Li‐Wen Hsu, Chih‐Kuang Yeh, Hsiang‐Hao Hsu, Chieh‐Cheng Huang
Format: Article
Language:English
Published: Wiley 2021-05-01
Series:Bioengineering & Translational Medicine
Subjects:
cell spheroids
cell therapy
glomerulus
kidney injury
podocyte
Online Access:https://doi.org/10.1002/btm2.10212

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