Pharmacological Blockade of PPARα Exacerbates Inflammatory Pain-Related Impairment of Spatial Memory in Rats

Pharmacological Blockade of PPARα Exacerbates Inflammatory Pain-Related Impairment of Spatial Memory in Rats

Peroxisome proliferator-activated receptors (PPARs) are ligand-dependent transcription factors that exist in three isoforms: PPARα, PPARβ/δ and PPARγ. Studies suggest that the PPAR signalling system may modulate pain, anxiety and cognition. The aim of the present study was to investigate whether end...

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Bibliographic Details
Main Authors:	Jessica C. Gaspar, Catherine Healy, Mehnaz I. Ferdousi, Michelle Roche, David P. Finn
Format:	Article
Language:	English
Published:	MDPI AG 2021-05-01
Series:	Biomedicines
Subjects:	peroxisome-proliferator activated receptor cognition anxiety spatial memory complete Freund adjuvant PEA
Online Access:	https://www.mdpi.com/2227-9059/9/6/610

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