PARP-1 Expression Influences Cancer Stem Cell Phenotype in Colorectal Cancer Depending on p53

PARP-1 Expression Influences Cancer Stem Cell Phenotype in Colorectal Cancer Depending on p53

Poly(ADP-ribose) polymerase-1 (PARP-1) is a protein involved in multiple physiological processes. Elevated PARP-1 expression has been found in several tumours, being associated with stemness and tumorigenesis. In colorectal cancer (CRC), some controversy among studies has been described. In this stu...

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Bibliographic Details
Main Authors:	Jose D. Puentes-Pardo, Sara Moreno-SanJuan, Jorge Casado, Julia Escudero-Feliu, David López-Pérez, Paula Sánchez-Uceta, Paula González-Novoa, Julio Gálvez, Ángel Carazo, Josefa León
Format:	Article
Language:	English
Published:	MDPI AG 2023-03-01
Series:	International Journal of Molecular Sciences
Subjects:	colorectal cancer PARP-1 cancer stem cells p53
Online Access:	https://www.mdpi.com/1422-0067/24/5/4787

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