The Anti-Depressive Effects of Hesperidin and the Relative Mechanisms Based on the NLRP3 Inflammatory Signaling Pathway

The Anti-Depressive Effects of Hesperidin and the Relative Mechanisms Based on the NLRP3 Inflammatory Signaling Pathway

There is increasing evidence showing that inflammation is associated with depression in humans. Hesperidin, a natural bioflavonoid, has performed excellent effects on depression. The aim of this research was to investigate the therapeutic effect of hesperidin on chronic unpredictable mild stress (CUM...

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Bibliographic Details
Main Authors: Lulu Xie, Zhimin Gu, Haizhao Liu, Beitian Jia, Yiyang Wang, Min Cao, Ruiwen Song, Zhaiyi Zhang, Yuhong Bian
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Pharmacology
Subjects:
depression
inflammation
microglia
NLRP3
hesperidin
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.01251/full

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