Minor Impact of A258D Mutation on Biochemical and Enzymatic Properties of <i>Leishmania infantum</i> GDP-Mannose Pyrophosphorylase

Minor Impact of A258D Mutation on Biochemical and Enzymatic Properties of <i>Leishmania infantum</i> GDP-Mannose Pyrophosphorylase

Background: Leishmaniasis, a vector-borne disease caused by the protozoan parasite from the genus <i>Leishmania</i>, is endemic to tropical and subtropical areas. Few treatments are available against leishmaniasis, with all presenting issues of toxicity, resistance, and/or cost. In this...

Full description

Bibliographic Details
Main Authors: Wei Mao, Noureddine Lazar, Herman van Tilbeurgh, Philippe M. Loiseau, Sébastien Pomel
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Microorganisms
Subjects:
GDP-mannose pyrophosphorylase
<i>Leishmania infantum</i>
enzyme properties
Online Access:https://www.mdpi.com/2076-2607/10/2/231

Similar Items

Similar Items