COMPARATIVE PHARMACOKINETICS AND EFFECT ON THE HEMODYNAMICS OF ORIGINAL AND GENERIC NEBIVOLOL IN HEALTHY VOLUNTEERS

COMPARATIVE PHARMACOKINETICS AND EFFECT ON THE HEMODYNAMICS OF ORIGINAL AND GENERIC NEBIVOLOL IN HEALTHY VOLUNTEERS

Beta-blockers are an important part of modern pharmacotherapy in cardiology. The introduction of generics into clinical practice requires clear evidence of bioequivalence to the original drug.Aim. To study the pharmacokinetics and effect on hemodynamic parameters of the original and a generic nebivo...

Description complète

Détails bibliographiques
Auteurs principaux:	E. I. Bambysheva, K. V. Isaeva, M. M. Makhinova, D. T. Guranda, V. G. Belolipetskaya
Format:	Article
Langue:	English
Publié:	Столичная издательская компания 2016-05-01
Collection:	Рациональная фармакотерапия в кардиологии
Sujets:	nebivolol pharmacokinetics healthy volunteers bioequivalence
Accès en ligne:	https://www.rpcardio.online/jour/article/view/1234

Documents similaires

The Effect Of Food On The Pharmacokinetic Properties And Bioequivalence Of Two Formulations Of Levocetirizine Dihydrochloride In Healthy Chinese Volunteers
par: Cheng Y, et autres
Publié: (2019-10-01)

Pharmacokinetics and bioequivalence of the generic and original dabigatran etexilate after a single dose in healthy volunteers
par: V. B. Vasilyuk, et autres
Publié: (2024-10-01)

Pharmacokinetics and bioequivalence of Ezetimibe tablet versus Ezetrol®:an open-label, randomized, two-sequence crossover study in healthy Chinese subjects
par: Feifei Sun, et autres
Publié: (2023-02-01)

BIOEQUIVALENCE STUDY OF GENERIC MOLNUPIRAVIR IN HEALTHY VOLUNTEERS
par: V. B. Vasilyuk, et autres
Publié: (2023-02-01)

Comparative bioavailability of a newly developed Irbesartan 300 mg containing preparation
par: Petrov Andrey D., et autres
Publié: (2018-01-01)

Pharmacokinetics of the total triterpenic fraction of centella asiatica after single and multiple administration to healthy volunteers. A new assay for asiatic acid/
par: Grimaldi, R.

Assessment of the influence of demographic and anthropometric indicators on the variability of pharmacokinetic parameters
par: V. B. Vasilyuk, et autres
Publié: (2024-06-01)

Bioequivalence study of generic nirmatrelvir in healthy volunteers
par: R. A. Oseshnyuk, et autres
Publié: (2023-05-01)

Pharmacokinetic and bioequivalence study of Telzap® Plus fixed-dose combination compared with MikardisPlus® in healthy volunteers after single administration
par: A. L. Khokhlov, et autres
Publié: (2023-01-01)

Sultiame pharmacokinetic profile in plasma and erythrocytes after single oral doses: A pilot study in healthy volunteers
par: Kim Dao, et autres
Publié: (2020-02-01)

Formulation and bioequivalence studies of choline alfoscerate tablet comparing with soft gelatin capsule in healthy male volunteers
par: Min MH, et autres
Publié: (2019-04-01)

Evaluation of Olaparib Tablet Safety and Pharmacokinetics in Healthy Chinese Male Subjects
par: Dong R, et autres
Publié: (2024-12-01)

Pharmacokinetics and pharmacodynamics of insulin lispro 25 versus the original preparation (Humalog®25) in Chinese healthy male volunteers
par: Mingxue Zhu, et autres
Publié: (2025-02-01)

Nebivolol-induced hepatoxicity: a case report
par: Lynn Srour, et autres
Publié: (2024-10-01)

Pharmacokinetic and bioequivalence study of Telzap® in comparison with Mikardis® in healthy subjects after single administrationl
par: A. L. Khokhlov, et autres
Publié: (2023-01-01)

Safety and pharmacokinetic properties of a new formulation of parenteral artesunate in healthy Thai volunteers
par: Joel Tarning, et autres
Publié: (2024-10-01)

Evaluation of Pharmacokinetics and Safety with Bioequivalence of Ibuprofen Sustained-Release Capsules of Two Formulations, in Chinese Healthy Volunteers: Bioequivalence Study
par: Huang C, et autres
Publié: (2023-06-01)

Application of rapid and simple liquid chromatography method for determination of bioequivalence of generic lamotrigine tablets in healthy Iranian volunteers
par: Samirasadat Abolmaali, et autres
Publié: (2015-07-01)

Application of rapid and simple liquid chromatography method for determination of bioequivalence of generic lamotrigine tablets in healthy Iranian volunteers
par: Samirasadat Abolmaali, et autres
Publié: (2015-09-01)

A Single Dose of Baicalin Has No Clinically Significant Effect on the Pharmacokinetics of Cyclosporine A in Healthy Chinese Volunteers
par: Ruijuan Liu, et autres
Publié: (2019-05-01)

Use of nebivolol in patients with mild and moderate hypertensive disease
par: L V Zhigunova, et autres
Publié: (2003-03-01)

Pharmacokinetics, safety, and immunogenicity of HLX03, an adalimumab biosimilar, compared with reference biologic in healthy Chinese male volunteers: Results of a randomized, double‐blind, parallel‐controlled, phase 1 study
par: Hong Zhang, et autres
Publié: (2021-04-01)

Bioequivalence and Pharmacokinetic Profiles of Generic and Branded Obeticholic Acid in Healthy Chinese Subjects Under Fasting and Fed Conditions
par: Wang MN, et autres
Publié: (2021-01-01)

Pharmacokinetics and Tolerability of Single and Multiple Intravenous Doses of Cefotetan Disodium in Healthy Chinese Volunteers
par: Liu J, et autres
Publié: (2020-02-01)

A randomized two-way crossover comparative pharmacokinetic study of two different tablet formulations containing ilaprazole in healthy human Indian volunteers
par: Shubhasis Dan, et autres
Publié: (2014-01-01)

Pharmacokinetics and bioavailability of single dose ibuprofen and pseudoephedrine alone or in combination: a randomized three-period, cross-over trial in healthy Indian volunteers
par: Prashant eKale
Publié: (2014-05-01)

NEBIVOLOL ROLE IN THE CORRECTION OF INTRACARDIAC HEMODYNAMICS IN PATIENTS WITH CHRONIC HEART FAILURE
par: R. L. Dzhanaeva, et autres
Publié: (2012-02-01)

Beneficial Effects of Nebivolol in Comparison with Atenolol on Safety and Tolerability in Essential Hypertension
par: Vivek V. Bhosale, et autres
Publié: (2014-06-01)

Bioequivalence and Pharmacokinetics Comparison of Two Formulations of Extended-Release Pentoxifylline Tablets in Healthy Subjects after Fasting and Fed Conditions
par: Jaafar J. Ibraheem Al-Tamimi
Publié: (2017-01-01)

Bioavailability and Pharmacokinetics of Once-Daily Amantadine Extended-Release Tablets in Healthy Volunteers: Results from Three Randomized, Crossover, Open-Label, Phase 1 Studies
par: Tina deVries, et autres
Publié: (2019-08-01)

Application of rapid and simple liquid chromatography method for determination of bioequivalence of generic lamotrigine tablets in healthy Iranian volunteers
par: Samira Sadat Abolmaali, et autres
Publié: (2015-09-01)

Tolerability, safety, and pharmacokinetics of a single intravenous administration of a novel recombinant humanized anti-interleukin-6 receptor monoclonal antibody in healthy Chinese volunteers
par: Xin Jiang, et autres
Publié: (2024-01-01)

Pharmacokinetics and Safety of Estradiol Valerate Tablet and Its Generic: A Phase 1 Bioequivalence Study in Healthy Chinese Postmenopausal Female Subjects
par: Zhang L, et autres
Publié: (2024-07-01)

Results of a phase I open randomized comparative crossover clinical trial to assess the safety and pharmacokinetics of Glurazyme® (imiglucerase) in comparison with the reference product in healthy volunteers
par: S. B. Fitilev, et autres
Publié: (2019-12-01)

Pharmacokinetics and bioequivalence of two formulations of mifepristone tablets in healthy Chinese subjects under fasting conditions: a single-center, open, randomized, single-dose, double-period, two-sequence, crossover trial
par: Yufeng Yan, et autres
Publié: (2024-10-01)

Nebivolol induced hyperkalemia: case report
par: Karmela Altabas, et autres
Publié: (2016-01-01)

Comparison of pharmacokinetics and safety between CE-fosphenytoin sodium, fosphenytoin sodium, and phenytoin sodium after intravenous and intramuscular administration in healthy volunteers
par: Xiaojiao Li, et autres
Publié: (2023-11-01)

Pharmacokinetics and Bioequivalence of Two Formulations of Valsartan 80 mg Capsules: A Randomized, Single Dose, 4-Period Crossover Study in Healthy Chinese Volunteers Under Fasting and Fed Conditions
par: Wu Q, et autres
Publié: (2020-10-01)

How to Achieve Sufficient Endogenous Insulin Suppression in Euglycemic Clamps Assessing the Pharmacokinetics and Pharmacodynamics of Long-Acting Insulin Preparations Employing Healthy Volunteers
par: Hui Liu, et autres
Publié: (2022-07-01)

Comparative pharmacokinetics of a fixed-dose combination vs concomitant administration of telmisartan and S-amlodipine in healthy adult volunteers
par: Oh M, et autres
Publié: (2017-12-01)