COMPARATIVE PHARMACOKINETICS AND EFFECT ON THE HEMODYNAMICS OF ORIGINAL AND GENERIC NEBIVOLOL IN HEALTHY VOLUNTEERS

COMPARATIVE PHARMACOKINETICS AND EFFECT ON THE HEMODYNAMICS OF ORIGINAL AND GENERIC NEBIVOLOL IN HEALTHY VOLUNTEERS

Beta-blockers are an important part of modern pharmacotherapy in cardiology. The introduction of generics into clinical practice requires clear evidence of bioequivalence to the original drug.Aim. To study the pharmacokinetics and effect on hemodynamic parameters of the original and a generic nebivo...

Полное описание

Библиографические подробности
Главные авторы:	E. I. Bambysheva, K. V. Isaeva, M. M. Makhinova, D. T. Guranda, V. G. Belolipetskaya
Формат:	Статья
Язык:	English
Опубликовано:	Столичная издательская компания 2016-05-01
Серии:	Рациональная фармакотерапия в кардиологии
Предметы:	nebivolol pharmacokinetics healthy volunteers bioequivalence
Online-ссылка:	https://www.rpcardio.online/jour/article/view/1234

Схожие документы

The Effect Of Food On The Pharmacokinetic Properties And Bioequivalence Of Two Formulations Of Levocetirizine Dihydrochloride In Healthy Chinese Volunteers
по: Cheng Y, и др.
Опубликовано: (2019-10-01)

Pharmacokinetics and bioequivalence of the generic and original dabigatran etexilate after a single dose in healthy volunteers
по: V. B. Vasilyuk, и др.
Опубликовано: (2024-10-01)

Pharmacokinetics and bioequivalence of Ezetimibe tablet versus Ezetrol®:an open-label, randomized, two-sequence crossover study in healthy Chinese subjects
по: Feifei Sun, и др.
Опубликовано: (2023-02-01)

BIOEQUIVALENCE STUDY OF GENERIC MOLNUPIRAVIR IN HEALTHY VOLUNTEERS
по: V. B. Vasilyuk, и др.
Опубликовано: (2023-02-01)

Comparative bioavailability of a newly developed Irbesartan 300 mg containing preparation
по: Petrov Andrey D., и др.
Опубликовано: (2018-01-01)

Pharmacokinetics of the total triterpenic fraction of centella asiatica after single and multiple administration to healthy volunteers. A new assay for asiatic acid/
по: Grimaldi, R.

Assessment of the influence of demographic and anthropometric indicators on the variability of pharmacokinetic parameters
по: V. B. Vasilyuk, и др.
Опубликовано: (2024-06-01)

Bioequivalence study of generic nirmatrelvir in healthy volunteers
по: R. A. Oseshnyuk, и др.
Опубликовано: (2023-05-01)

Pharmacokinetic and bioequivalence study of Telzap® Plus fixed-dose combination compared with MikardisPlus® in healthy volunteers after single administration
по: A. L. Khokhlov, и др.
Опубликовано: (2023-01-01)

Sultiame pharmacokinetic profile in plasma and erythrocytes after single oral doses: A pilot study in healthy volunteers
по: Kim Dao, и др.
Опубликовано: (2020-02-01)

Formulation and bioequivalence studies of choline alfoscerate tablet comparing with soft gelatin capsule in healthy male volunteers
по: Min MH, и др.
Опубликовано: (2019-04-01)

Evaluation of Olaparib Tablet Safety and Pharmacokinetics in Healthy Chinese Male Subjects
по: Dong R, и др.
Опубликовано: (2024-12-01)

Pharmacokinetics and pharmacodynamics of insulin lispro 25 versus the original preparation (Humalog®25) in Chinese healthy male volunteers
по: Mingxue Zhu, и др.
Опубликовано: (2025-02-01)

Nebivolol-induced hepatoxicity: a case report
по: Lynn Srour, и др.
Опубликовано: (2024-10-01)

Pharmacokinetic and bioequivalence study of Telzap® in comparison with Mikardis® in healthy subjects after single administrationl
по: A. L. Khokhlov, и др.
Опубликовано: (2023-01-01)

Safety and pharmacokinetic properties of a new formulation of parenteral artesunate in healthy Thai volunteers
по: Joel Tarning, и др.
Опубликовано: (2024-10-01)

Evaluation of Pharmacokinetics and Safety with Bioequivalence of Ibuprofen Sustained-Release Capsules of Two Formulations, in Chinese Healthy Volunteers: Bioequivalence Study
по: Huang C, и др.
Опубликовано: (2023-06-01)

Application of rapid and simple liquid chromatography method for determination of bioequivalence of generic lamotrigine tablets in healthy Iranian volunteers
по: Samirasadat Abolmaali, и др.
Опубликовано: (2015-07-01)

Application of rapid and simple liquid chromatography method for determination of bioequivalence of generic lamotrigine tablets in healthy Iranian volunteers
по: Samirasadat Abolmaali, и др.
Опубликовано: (2015-09-01)

A Single Dose of Baicalin Has No Clinically Significant Effect on the Pharmacokinetics of Cyclosporine A in Healthy Chinese Volunteers
по: Ruijuan Liu, и др.
Опубликовано: (2019-05-01)

Use of nebivolol in patients with mild and moderate hypertensive disease
по: L V Zhigunova, и др.
Опубликовано: (2003-03-01)

Pharmacokinetics, safety, and immunogenicity of HLX03, an adalimumab biosimilar, compared with reference biologic in healthy Chinese male volunteers: Results of a randomized, double‐blind, parallel‐controlled, phase 1 study
по: Hong Zhang, и др.
Опубликовано: (2021-04-01)

Bioequivalence and Pharmacokinetic Profiles of Generic and Branded Obeticholic Acid in Healthy Chinese Subjects Under Fasting and Fed Conditions
по: Wang MN, и др.
Опубликовано: (2021-01-01)

Pharmacokinetics and Tolerability of Single and Multiple Intravenous Doses of Cefotetan Disodium in Healthy Chinese Volunteers
по: Liu J, и др.
Опубликовано: (2020-02-01)

A randomized two-way crossover comparative pharmacokinetic study of two different tablet formulations containing ilaprazole in healthy human Indian volunteers
по: Shubhasis Dan, и др.
Опубликовано: (2014-01-01)

Pharmacokinetics and bioavailability of single dose ibuprofen and pseudoephedrine alone or in combination: a randomized three-period, cross-over trial in healthy Indian volunteers
по: Prashant eKale
Опубликовано: (2014-05-01)

NEBIVOLOL ROLE IN THE CORRECTION OF INTRACARDIAC HEMODYNAMICS IN PATIENTS WITH CHRONIC HEART FAILURE
по: R. L. Dzhanaeva, и др.
Опубликовано: (2012-02-01)

Beneficial Effects of Nebivolol in Comparison with Atenolol on Safety and Tolerability in Essential Hypertension
по: Vivek V. Bhosale, и др.
Опубликовано: (2014-06-01)

Bioequivalence and Pharmacokinetics Comparison of Two Formulations of Extended-Release Pentoxifylline Tablets in Healthy Subjects after Fasting and Fed Conditions
по: Jaafar J. Ibraheem Al-Tamimi
Опубликовано: (2017-01-01)

Bioavailability and Pharmacokinetics of Once-Daily Amantadine Extended-Release Tablets in Healthy Volunteers: Results from Three Randomized, Crossover, Open-Label, Phase 1 Studies
по: Tina deVries, и др.
Опубликовано: (2019-08-01)

Application of rapid and simple liquid chromatography method for determination of bioequivalence of generic lamotrigine tablets in healthy Iranian volunteers
по: Samira Sadat Abolmaali, и др.
Опубликовано: (2015-09-01)

Tolerability, safety, and pharmacokinetics of a single intravenous administration of a novel recombinant humanized anti-interleukin-6 receptor monoclonal antibody in healthy Chinese volunteers
по: Xin Jiang, и др.
Опубликовано: (2024-01-01)

Pharmacokinetics and Safety of Estradiol Valerate Tablet and Its Generic: A Phase 1 Bioequivalence Study in Healthy Chinese Postmenopausal Female Subjects
по: Zhang L, и др.
Опубликовано: (2024-07-01)

Results of a phase I open randomized comparative crossover clinical trial to assess the safety and pharmacokinetics of Glurazyme® (imiglucerase) in comparison with the reference product in healthy volunteers
по: S. B. Fitilev, и др.
Опубликовано: (2019-12-01)

Pharmacokinetics and bioequivalence of two formulations of mifepristone tablets in healthy Chinese subjects under fasting conditions: a single-center, open, randomized, single-dose, double-period, two-sequence, crossover trial
по: Yufeng Yan, и др.
Опубликовано: (2024-10-01)

Nebivolol induced hyperkalemia: case report
по: Karmela Altabas, и др.
Опубликовано: (2016-01-01)

Comparison of pharmacokinetics and safety between CE-fosphenytoin sodium, fosphenytoin sodium, and phenytoin sodium after intravenous and intramuscular administration in healthy volunteers
по: Xiaojiao Li, и др.
Опубликовано: (2023-11-01)

Pharmacokinetics and Bioequivalence of Two Formulations of Valsartan 80 mg Capsules: A Randomized, Single Dose, 4-Period Crossover Study in Healthy Chinese Volunteers Under Fasting and Fed Conditions
по: Wu Q, и др.
Опубликовано: (2020-10-01)

How to Achieve Sufficient Endogenous Insulin Suppression in Euglycemic Clamps Assessing the Pharmacokinetics and Pharmacodynamics of Long-Acting Insulin Preparations Employing Healthy Volunteers
по: Hui Liu, и др.
Опубликовано: (2022-07-01)

Comparative pharmacokinetics of a fixed-dose combination vs concomitant administration of telmisartan and S-amlodipine in healthy adult volunteers
по: Oh M, и др.
Опубликовано: (2017-12-01)