A new target of radiotherapy combined with immunotherapy: regulatory T cells
Radiotherapy is one important treatment for malignant tumours. It is widely believed today that radiotherapy has not only been used as a local tumour treatment method, but also can induce systemic anti-tumour responses by influencing the tumour microenvironment, but its efficacy is limited by the tu...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2024-01-01
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| Series: | Frontiers in Immunology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fimmu.2023.1330099/full |
| _version_ | 1797362411422875648 |
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| author | Dongmei Song Yun Ding |
| author_facet | Dongmei Song Yun Ding |
| author_sort | Dongmei Song |
| collection | DOAJ |
| description | Radiotherapy is one important treatment for malignant tumours. It is widely believed today that radiotherapy has not only been used as a local tumour treatment method, but also can induce systemic anti-tumour responses by influencing the tumour microenvironment, but its efficacy is limited by the tumour immunosuppression microenvironment. With the advancement of technology, immunotherapy has entered a golden age of rapid development, gradually occupying a place in clinical tumour treatment. Regulatory T cells (Tregs) widely distributing in the tumour microenvironment play an important role in mediating tumour development. This article analyzes immunotherapy, the interaction between Tregs, tumours and radiotherapy. It briefly introduces immunotherapies targeting Tregs, aiming to provide new strategies for radiotherapy combined with Immunotherapy. |
| first_indexed | 2024-03-08T16:07:38Z |
| format | Article |
| id | doaj.art-aabad67328f64ecbadd8c19f55d15b9f |
| institution | Directory Open Access Journal |
| issn | 1664-3224 |
| language | English |
| last_indexed | 2024-03-08T16:07:38Z |
| publishDate | 2024-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Immunology |
| spelling | doaj.art-aabad67328f64ecbadd8c19f55d15b9f2024-01-08T05:07:15ZengFrontiers Media S.A.Frontiers in Immunology1664-32242024-01-011410.3389/fimmu.2023.13300991330099A new target of radiotherapy combined with immunotherapy: regulatory T cellsDongmei SongYun DingRadiotherapy is one important treatment for malignant tumours. It is widely believed today that radiotherapy has not only been used as a local tumour treatment method, but also can induce systemic anti-tumour responses by influencing the tumour microenvironment, but its efficacy is limited by the tumour immunosuppression microenvironment. With the advancement of technology, immunotherapy has entered a golden age of rapid development, gradually occupying a place in clinical tumour treatment. Regulatory T cells (Tregs) widely distributing in the tumour microenvironment play an important role in mediating tumour development. This article analyzes immunotherapy, the interaction between Tregs, tumours and radiotherapy. It briefly introduces immunotherapies targeting Tregs, aiming to provide new strategies for radiotherapy combined with Immunotherapy.https://www.frontiersin.org/articles/10.3389/fimmu.2023.1330099/fullradiotherapyTregsimmunotherapyradiosensitivityimmune microenvironment |
| spellingShingle | Dongmei Song Yun Ding A new target of radiotherapy combined with immunotherapy: regulatory T cells Frontiers in Immunology radiotherapy Tregs immunotherapy radiosensitivity immune microenvironment |
| title | A new target of radiotherapy combined with immunotherapy: regulatory T cells |
| title_full | A new target of radiotherapy combined with immunotherapy: regulatory T cells |
| title_fullStr | A new target of radiotherapy combined with immunotherapy: regulatory T cells |
| title_full_unstemmed | A new target of radiotherapy combined with immunotherapy: regulatory T cells |
| title_short | A new target of radiotherapy combined with immunotherapy: regulatory T cells |
| title_sort | new target of radiotherapy combined with immunotherapy regulatory t cells |
| topic | radiotherapy Tregs immunotherapy radiosensitivity immune microenvironment |
| url | https://www.frontiersin.org/articles/10.3389/fimmu.2023.1330099/full |
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