Cell Death in the Tumor Microenvironment: Implications for Cancer Immunotherapy

Cell Death in the Tumor Microenvironment: Implications for Cancer Immunotherapy

The physiological fate of cells that die by apoptosis is their prompt and efficient removal by efferocytosis. During these processes, apoptotic cells release intracellular constituents that include purine nucleotides, lysophosphatidylcholine (LPC), and Sphingosine-1-phosphate (S1P) that induce migra...

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Bibliographic Details
Main Authors: Varsha Gadiyar, Kevin C. Lahey, David Calianese, Connor Devoe, Dhriti Mehta, Kristy Bono, Samuel Desind, Viralkumar Davra, Raymond B. Birge
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Cells
Subjects:
apoptosis
efferocytosis
compensatory proliferation
immune evasion
cancer
phosphatidylserine (PS)
Online Access:https://www.mdpi.com/2073-4409/9/10/2207

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