FGF2 alters macrophage polarization, tumour immunity and growth and can be targeted during radiotherapy
Macrophages contribute to tumour progression and response to therapy. Here, the authors show that absence of FGF2 in the tumour microenvironment reduces tumour growth and enhances the anti-tumour immune response by altering macrophage polarization. As a result, disruption of this macrophage programm...
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2020-08-01
|
| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-020-17914-x |