Patients’ and Physicians’ Preferences for Systemic Psoriasis Treatments: A Nationwide Comparative Discrete Choice Experiment (PsoCompare)

Systemic antipsoriatic treatment options are increasing rapidly. The aim of this nationwide discrete choice experiment was to compare patients’ (n = 222) and physicians’ (n = 78) preferences for outcome and process attributes of systemic antipsoriatics using Relative Importance Scores (RIS). Both gr...

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Main Authors: Marthe-Lisa Schaarschmidt, Raphael Herr, Mandy Gutknecht, Katharina Wroblewska, Sascha Gerdes, Michael Sticherling, Matthias Augustin, Wiebke K. Peitsch
Format: Article
Language:English
Published: Medical Journals Sweden 2017-11-01
Series:Acta Dermato-Venereologica
Subjects:
Online Access: https://www.medicaljournals.se/acta/content/html/10.2340/00015555-2834
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author Marthe-Lisa Schaarschmidt
Raphael Herr
Mandy Gutknecht
Katharina Wroblewska
Sascha Gerdes
Michael Sticherling
Matthias Augustin
Wiebke K. Peitsch
author_facet Marthe-Lisa Schaarschmidt
Raphael Herr
Mandy Gutknecht
Katharina Wroblewska
Sascha Gerdes
Michael Sticherling
Matthias Augustin
Wiebke K. Peitsch
author_sort Marthe-Lisa Schaarschmidt
collection DOAJ
description Systemic antipsoriatic treatment options are increasing rapidly. The aim of this nationwide discrete choice experiment was to compare patients’ (n = 222) and physicians’ (n = 78) preferences for outcome and process attributes of systemic antipsoriatics using Relative Importance Scores (RIS). Both groups considered Psoriasis Area and Severity Index 90 (PASI 90) to be most important (RIS 21.4 and 20.8, respectively). Moreover, patients were highly concerned about mild and severe adverse events (RIS = 18.2 and 14.2), physicians about severe adverse events (RIS = 14.9) and cost (RIS = 13.8). Compared to physicians, patients worried more about mild adverse events and treatment location, but less about cost and frequency of laboratory tests. Physicians’ preferences were influenced by work experience and percentage of biological prescriptions, patients’ preferences by age, disease duration and severity. Older and less severely affected patients recruited via a patient organization focused more on safety, but less on efficacy and time until response than did patients from study centres. In conclusion, these differences in trade-offs should be integrated into a shared decision-making.
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spelling doaj.art-aac332f3a1c74da8aac0952afa7e77d22022-12-21T19:23:37ZengMedical Journals SwedenActa Dermato-Venereologica0001-55551651-20572017-11-0198220020510.2340/00015555-28345107Patients’ and Physicians’ Preferences for Systemic Psoriasis Treatments: A Nationwide Comparative Discrete Choice Experiment (PsoCompare)Marthe-Lisa Schaarschmidt0Raphael HerrMandy GutknechtKatharina WroblewskaSascha GerdesMichael SticherlingMatthias AugustinWiebke K. Peitsch Department of Dermatology, University Medical Center Mannheim, Heidelberg University, DE-68135 Mannheim, Germany. Systemic antipsoriatic treatment options are increasing rapidly. The aim of this nationwide discrete choice experiment was to compare patients’ (n = 222) and physicians’ (n = 78) preferences for outcome and process attributes of systemic antipsoriatics using Relative Importance Scores (RIS). Both groups considered Psoriasis Area and Severity Index 90 (PASI 90) to be most important (RIS 21.4 and 20.8, respectively). Moreover, patients were highly concerned about mild and severe adverse events (RIS = 18.2 and 14.2), physicians about severe adverse events (RIS = 14.9) and cost (RIS = 13.8). Compared to physicians, patients worried more about mild adverse events and treatment location, but less about cost and frequency of laboratory tests. Physicians’ preferences were influenced by work experience and percentage of biological prescriptions, patients’ preferences by age, disease duration and severity. Older and less severely affected patients recruited via a patient organization focused more on safety, but less on efficacy and time until response than did patients from study centres. In conclusion, these differences in trade-offs should be integrated into a shared decision-making. https://www.medicaljournals.se/acta/content/html/10.2340/00015555-2834 biologicalsconjointanalysisdiscretechoiceexperimentpreferencespsoriasissystemictreatment
spellingShingle Marthe-Lisa Schaarschmidt
Raphael Herr
Mandy Gutknecht
Katharina Wroblewska
Sascha Gerdes
Michael Sticherling
Matthias Augustin
Wiebke K. Peitsch
Patients’ and Physicians’ Preferences for Systemic Psoriasis Treatments: A Nationwide Comparative Discrete Choice Experiment (PsoCompare)
Acta Dermato-Venereologica
biologicals
conjointanalysis
discretechoiceexperiment
preferences
psoriasis
systemictreatment
title Patients’ and Physicians’ Preferences for Systemic Psoriasis Treatments: A Nationwide Comparative Discrete Choice Experiment (PsoCompare)
title_full Patients’ and Physicians’ Preferences for Systemic Psoriasis Treatments: A Nationwide Comparative Discrete Choice Experiment (PsoCompare)
title_fullStr Patients’ and Physicians’ Preferences for Systemic Psoriasis Treatments: A Nationwide Comparative Discrete Choice Experiment (PsoCompare)
title_full_unstemmed Patients’ and Physicians’ Preferences for Systemic Psoriasis Treatments: A Nationwide Comparative Discrete Choice Experiment (PsoCompare)
title_short Patients’ and Physicians’ Preferences for Systemic Psoriasis Treatments: A Nationwide Comparative Discrete Choice Experiment (PsoCompare)
title_sort patients and physicians preferences for systemic psoriasis treatments a nationwide comparative discrete choice experiment psocompare
topic biologicals
conjointanalysis
discretechoiceexperiment
preferences
psoriasis
systemictreatment
url https://www.medicaljournals.se/acta/content/html/10.2340/00015555-2834
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