Cytomegalovirus and varicella zoster virus coinfection-associated central hypoventilation syndrome (Ondine's Curse)
Central hypoventilation syndrome (CHS) is a rare condition resulting from damage to the respiratory centers in the central nervous system (CNS). It can be congenital or acquired and can cause hypoventilation, inadequate gas exchange, and respiratory failure, often during sleep but sometimes even whi...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2024-03-01
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| Series: | eNeurologicalSci |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405650223000461 |
| _version_ | 1827620770162933760 |
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| author | Marine Isakadze Benjamin Zwain Alan J. Velander Jesus Lovera |
| author_facet | Marine Isakadze Benjamin Zwain Alan J. Velander Jesus Lovera |
| author_sort | Marine Isakadze |
| collection | DOAJ |
| description | Central hypoventilation syndrome (CHS) is a rare condition resulting from damage to the respiratory centers in the central nervous system (CNS). It can be congenital or acquired and can cause hypoventilation, inadequate gas exchange, and respiratory failure, often during sleep but sometimes even while awake. CHS can lead to respiratory failure and life-threatening complications if not identified promptly. In this report, we present a rare case of a patient with human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS), who developed CHS likely due to an opportunistic infection by cytomegalovirus (CMV) and varicella zoster virus (VZV), manifesting as a lesion in the medullary respiratory nuclei. After treatment with ganciclovir, the patient showed clinical improvement, and his medullary lesion resolved. |
| first_indexed | 2024-03-09T10:52:38Z |
| format | Article |
| id | doaj.art-aac6ba593e0540b1a056318cc1603ee0 |
| institution | Directory Open Access Journal |
| issn | 2405-6502 |
| language | English |
| last_indexed | 2024-03-09T10:52:38Z |
| publishDate | 2024-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | eNeurologicalSci |
| spelling | doaj.art-aac6ba593e0540b1a056318cc1603ee02023-12-01T05:02:24ZengElseviereNeurologicalSci2405-65022024-03-0134100488Cytomegalovirus and varicella zoster virus coinfection-associated central hypoventilation syndrome (Ondine's Curse)Marine Isakadze0Benjamin Zwain1Alan J. Velander2Jesus Lovera3LSUHSC Neurology Residency Program, United States of America; Corresponding author.LSUHSC Neurology Residency Program, United States of AmericaLSUHSC Neurology and Neurosurgery Residency Programs, United States of AmericaLSUHSC Neurology Residency Program, United States of AmericaCentral hypoventilation syndrome (CHS) is a rare condition resulting from damage to the respiratory centers in the central nervous system (CNS). It can be congenital or acquired and can cause hypoventilation, inadequate gas exchange, and respiratory failure, often during sleep but sometimes even while awake. CHS can lead to respiratory failure and life-threatening complications if not identified promptly. In this report, we present a rare case of a patient with human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS), who developed CHS likely due to an opportunistic infection by cytomegalovirus (CMV) and varicella zoster virus (VZV), manifesting as a lesion in the medullary respiratory nuclei. After treatment with ganciclovir, the patient showed clinical improvement, and his medullary lesion resolved.http://www.sciencedirect.com/science/article/pii/S2405650223000461Central hypoventilation syndromeCytomegalovirusCMVVaricella zoster virusVZVBrainstem |
| spellingShingle | Marine Isakadze Benjamin Zwain Alan J. Velander Jesus Lovera Cytomegalovirus and varicella zoster virus coinfection-associated central hypoventilation syndrome (Ondine's Curse) eNeurologicalSci Central hypoventilation syndrome Cytomegalovirus CMV Varicella zoster virus VZV Brainstem |
| title | Cytomegalovirus and varicella zoster virus coinfection-associated central hypoventilation syndrome (Ondine's Curse) |
| title_full | Cytomegalovirus and varicella zoster virus coinfection-associated central hypoventilation syndrome (Ondine's Curse) |
| title_fullStr | Cytomegalovirus and varicella zoster virus coinfection-associated central hypoventilation syndrome (Ondine's Curse) |
| title_full_unstemmed | Cytomegalovirus and varicella zoster virus coinfection-associated central hypoventilation syndrome (Ondine's Curse) |
| title_short | Cytomegalovirus and varicella zoster virus coinfection-associated central hypoventilation syndrome (Ondine's Curse) |
| title_sort | cytomegalovirus and varicella zoster virus coinfection associated central hypoventilation syndrome ondine s curse |
| topic | Central hypoventilation syndrome Cytomegalovirus CMV Varicella zoster virus VZV Brainstem |
| url | http://www.sciencedirect.com/science/article/pii/S2405650223000461 |
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