MiR-155-5p Elevated by Ochratoxin A Induces Intestinal Fibrosis and Epithelial-to-Mesenchymal Transition through TGF-β Regulated Signaling Pathway In Vitro and In Vivo

MiR-155-5p Elevated by Ochratoxin A Induces Intestinal Fibrosis and Epithelial-to-Mesenchymal Transition through TGF-β Regulated Signaling Pathway In Vitro and In Vivo

Ochratoxin A (OTA) is a mycotoxin that induces fibrosis and epithelial-to-mesenchymal transitions (EMT) in kidneys and livers. It enters our bodies through food consumption, where it is absorbed in the intestines. However, the impact of OTA on the intestines is yet to be studied. MicroRNA (miRNAs) a...

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Bibliographic Details
Main Authors: Kyu Hyun Rhee, Seon Ah Yang, Min Cheol Pyo, Jae-Min Lim, Kwang-Won Lee
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Toxins
Subjects:
ochratoxin A
miR-155-5p
intestinal fibrosis
TGF-β
EMT
Online Access:https://www.mdpi.com/2072-6651/15/7/473

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