Comparative Upper Respiratory Tract Transcriptomic Profiling Reveals a Potential Role of Early Activation of Interferon Pathway in Severe COVID-19

Comparative Upper Respiratory Tract Transcriptomic Profiling Reveals a Potential Role of Early Activation of Interferon Pathway in Severe COVID-19

Infection with SARS-CoV-2 results in Coronavirus disease 2019 (COVID-19) is known to cause mild to acute respiratory infection and sometimes progress towards respiratory failure and death. The mechanisms driving the progression of the disease and accumulation of high viral load in the lungs without...

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Bibliographic Details
Main Authors: Shabir A. Bhat, Tomohiro Shibata, Matthew Leong, Jasmine Plummer, Eric Vail, Zakir Khan
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Viruses
Subjects:
COVID-19
RNA-Seq
IFN-I response
inflammation
viral infection
host-pathogen interactions
Online Access:https://www.mdpi.com/1999-4915/14/10/2182

Internet

https://www.mdpi.com/1999-4915/14/10/2182

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