Chemogenomics Knowledgebased Polypharmacology Analyses of Drug Abuse Related G-Protein Coupled Receptors and Their Ligands

Chemogenomics Knowledgebased Polypharmacology Analyses of Drug Abuse Related G-Protein Coupled Receptors and Their Ligands

Drug abuse (DA) and addiction is a complex illness, broadly viewed as a neurobiological impairment with genetic and environmental factors that influence its development and manifestation. Abused substances can disrupt the activity of neurons by interacting with many proteins, particularly G-protein...

Full description

Bibliographic Details
Main Authors: Xiang-Qun eXie, Lirong eWang, haibin eLiu, Qin eOuyang, Cheng eFang, Weiwei eSu
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-02-01
Series:Frontiers in Pharmacology
Subjects:
GPCRs
Drug abuse
Chemogenomics
polypharmacology
Polydrug addiction
Cloud Computation
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2014.00003/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphar.2014.00003/full

Similar Items