Performance of Ultrasonography Compared to Conventional Radiography for the Diagnosis of Osteoarthritis in Patients With Knee Pain
Purpose: To investigate the performance of ultrasonography (US) for the detection of knee osteoarthritis (OA) in patients suffering from knee pain, compared to conventional radiographs.Methods: Cross-sectional study performed at a university teaching hospital. Consecutive patients complaining of uni...
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Frontiers Media S.A.
2020-07-01
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| Series: | Frontiers in Medicine |
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| Online Access: | https://www.frontiersin.org/article/10.3389/fmed.2020.00319/full |
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| author | Martin Brom Ignacio J. Gandino Johana B. Zacariaz Hereter Marina Scolnik Florencia B. Mollerach Leandro G. Ferreyra Garrott Josefina Marin Santiago O. Ruta Javier E. Rosa Ricardo D. García-Mónaco Enrique R. Soriano |
| author_facet | Martin Brom Ignacio J. Gandino Johana B. Zacariaz Hereter Marina Scolnik Florencia B. Mollerach Leandro G. Ferreyra Garrott Josefina Marin Santiago O. Ruta Javier E. Rosa Ricardo D. García-Mónaco Enrique R. Soriano |
| author_sort | Martin Brom |
| collection | DOAJ |
| description | Purpose: To investigate the performance of ultrasonography (US) for the detection of knee osteoarthritis (OA) in patients suffering from knee pain, compared to conventional radiographs.Methods: Cross-sectional study performed at a university teaching hospital. Consecutive patients complaining of unilateral or bilateral mechanical knee pain who signed an informed consent were included. All patients underwent simultaneously an ultrasonographic and a radiographic evaluation of the knee. Exclusion criteria were age under 18 years, prior diagnosis of knee OA, diagnosis of inflammatory arthritis, history of knee surgery or trauma, severe knee deformities, and corticosteroid injection within the last 2 months. The diagnostic properties of US for the detection of knee OA were evaluated using radiological data as the reference method. Evaluated test properties were sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and the positive and negative likelihood ratio (LR+ and LR–).Results: Three-hundred twenty-two knees (281 patients) were included. Radiographic degenerative changes were present in 56.8% (183) of the evaluated knees. Regarding the diagnostic properties of the US, the presence of either osteophytes or the compromise of the femoral hyaline cartilage had the best sensitivity to detect OA (95%), with a NPV of 92% and a LR– of 0,07, while the combined identification of osteophytes and compromise of the femoral hyaline cartilage had the best specificity (94%), with 94% PPV and a LR+ of 13.Conclusion: US demonstrated an excellent sensitivity with an adequate specificity for the detection of radiographic knee OA. |
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| issn | 2296-858X |
| language | English |
| last_indexed | 2024-12-12T23:50:45Z |
| publishDate | 2020-07-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Medicine |
| spelling | doaj.art-aacdc05a99ac44709058bd685e34a5082022-12-22T00:06:42ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2020-07-01710.3389/fmed.2020.00319544834Performance of Ultrasonography Compared to Conventional Radiography for the Diagnosis of Osteoarthritis in Patients With Knee PainMartin Brom0Ignacio J. Gandino1Johana B. Zacariaz Hereter2Marina Scolnik3Florencia B. Mollerach4Leandro G. Ferreyra Garrott5Josefina Marin6Santiago O. Ruta7Javier E. Rosa8Ricardo D. García-Mónaco9Enrique R. Soriano10Rheumatology Department, Hospital Italiano de Buenos Aires, Buenos Aires, ArgentinaRheumatology Department, Hospital Italiano de Buenos Aires, Buenos Aires, ArgentinaRheumatology Department, Hospital Italiano de Buenos Aires, Buenos Aires, ArgentinaRheumatology Department, Hospital Italiano de Buenos Aires, Buenos Aires, ArgentinaRheumatology Department, Hospital Italiano de Buenos Aires, Buenos Aires, ArgentinaRheumatology Department, Hospital Italiano de Buenos Aires, Buenos Aires, ArgentinaRheumatology Department, Hospital Italiano de Buenos Aires, Buenos Aires, ArgentinaRheumatology Department, Hospital Italiano de Buenos Aires, Buenos Aires, ArgentinaRheumatology Department, Hospital Italiano de Buenos Aires, Buenos Aires, ArgentinaRadiology Department, Hospital Italiano de Buenos Aires, Buenos Aires, ArgentinaRheumatology Department, Hospital Italiano de Buenos Aires, Buenos Aires, ArgentinaPurpose: To investigate the performance of ultrasonography (US) for the detection of knee osteoarthritis (OA) in patients suffering from knee pain, compared to conventional radiographs.Methods: Cross-sectional study performed at a university teaching hospital. Consecutive patients complaining of unilateral or bilateral mechanical knee pain who signed an informed consent were included. All patients underwent simultaneously an ultrasonographic and a radiographic evaluation of the knee. Exclusion criteria were age under 18 years, prior diagnosis of knee OA, diagnosis of inflammatory arthritis, history of knee surgery or trauma, severe knee deformities, and corticosteroid injection within the last 2 months. The diagnostic properties of US for the detection of knee OA were evaluated using radiological data as the reference method. Evaluated test properties were sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and the positive and negative likelihood ratio (LR+ and LR–).Results: Three-hundred twenty-two knees (281 patients) were included. Radiographic degenerative changes were present in 56.8% (183) of the evaluated knees. Regarding the diagnostic properties of the US, the presence of either osteophytes or the compromise of the femoral hyaline cartilage had the best sensitivity to detect OA (95%), with a NPV of 92% and a LR– of 0,07, while the combined identification of osteophytes and compromise of the femoral hyaline cartilage had the best specificity (94%), with 94% PPV and a LR+ of 13.Conclusion: US demonstrated an excellent sensitivity with an adequate specificity for the detection of radiographic knee OA.https://www.frontiersin.org/article/10.3389/fmed.2020.00319/fullradiography (D011859)ultrasonography (D014463)osteoarthritis (D010003)knee osteoarthritis (D020370)diagnostic imaging (D003952) |
| spellingShingle | Martin Brom Ignacio J. Gandino Johana B. Zacariaz Hereter Marina Scolnik Florencia B. Mollerach Leandro G. Ferreyra Garrott Josefina Marin Santiago O. Ruta Javier E. Rosa Ricardo D. García-Mónaco Enrique R. Soriano Performance of Ultrasonography Compared to Conventional Radiography for the Diagnosis of Osteoarthritis in Patients With Knee Pain Frontiers in Medicine radiography (D011859) ultrasonography (D014463) osteoarthritis (D010003) knee osteoarthritis (D020370) diagnostic imaging (D003952) |
| title | Performance of Ultrasonography Compared to Conventional Radiography for the Diagnosis of Osteoarthritis in Patients With Knee Pain |
| title_full | Performance of Ultrasonography Compared to Conventional Radiography for the Diagnosis of Osteoarthritis in Patients With Knee Pain |
| title_fullStr | Performance of Ultrasonography Compared to Conventional Radiography for the Diagnosis of Osteoarthritis in Patients With Knee Pain |
| title_full_unstemmed | Performance of Ultrasonography Compared to Conventional Radiography for the Diagnosis of Osteoarthritis in Patients With Knee Pain |
| title_short | Performance of Ultrasonography Compared to Conventional Radiography for the Diagnosis of Osteoarthritis in Patients With Knee Pain |
| title_sort | performance of ultrasonography compared to conventional radiography for the diagnosis of osteoarthritis in patients with knee pain |
| topic | radiography (D011859) ultrasonography (D014463) osteoarthritis (D010003) knee osteoarthritis (D020370) diagnostic imaging (D003952) |
| url | https://www.frontiersin.org/article/10.3389/fmed.2020.00319/full |
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