Liver transplantation in an adult patient with hepatocellular carcinoma following liver cirrhosis as a complication of the Fontan procedure -A case report-
Background Fontan-associated liver disease (FALD) is a hepatic disorder caused by hemodynamic changes and systemic venous congestion following the Fontan procedure. FALD includes liver cirrhosis and hepatocellular carcinoma (HCC), both of which may require liver transplantation (LT). However, the Fo...
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| Format: | Article |
| Language: | English |
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Korean Society of Anesthesiologists
2020-10-01
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| Series: | Anesthesia and Pain Medicine |
| Subjects: | |
| Online Access: | http://www.anesth-pain-med.org/upload/pdf/apm-20037.pdf |
| _version_ | 1797825476539973632 |
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| author | Min-kyung Cho Ji-Hye Kwon Mi Sook Gwak Jae-Won Joh JiYun Hwang Gaab Soo Kim |
| author_facet | Min-kyung Cho Ji-Hye Kwon Mi Sook Gwak Jae-Won Joh JiYun Hwang Gaab Soo Kim |
| author_sort | Min-kyung Cho |
| collection | DOAJ |
| description | Background Fontan-associated liver disease (FALD) is a hepatic disorder caused by hemodynamic changes and systemic venous congestion following the Fontan procedure. FALD includes liver cirrhosis and hepatocellular carcinoma (HCC), both of which may require liver transplantation (LT). However, the Fontan circulation, characterized by elevated central venous pressure and reduced cardiac output, is a challenging issue for surgeons and anesthesiologists. Case We report a living-donor LT for the treatment of HCC. The patient was a 24-year-old male who underwent the Fontan procedure for pulmonary atresia and right ventricle hypoplasia. We focused on maintaining enough blood volume for cardiac output without causing pulmonary edema, as the patient is not well adapted to changes in volume. Owing to a multidisciplinary approach, the surgery was successfully performed without fatal adverse events. Conclusions To our knowledge, this is the first case of isolated LT in a recipient who became an adult after having undergone the Fontan procedure. |
| first_indexed | 2024-03-13T10:54:35Z |
| format | Article |
| id | doaj.art-aace8f60c7c4477e992734cb15066659 |
| institution | Directory Open Access Journal |
| issn | 1975-5171 2383-7977 |
| language | English |
| last_indexed | 2024-03-13T10:54:35Z |
| publishDate | 2020-10-01 |
| publisher | Korean Society of Anesthesiologists |
| record_format | Article |
| series | Anesthesia and Pain Medicine |
| spelling | doaj.art-aace8f60c7c4477e992734cb150666592023-05-17T05:41:40ZengKorean Society of AnesthesiologistsAnesthesia and Pain Medicine1975-51712383-79772020-10-0115446647110.17085/apm.200371047Liver transplantation in an adult patient with hepatocellular carcinoma following liver cirrhosis as a complication of the Fontan procedure -A case report-Min-kyung Cho0Ji-Hye Kwon1Mi Sook Gwak2Jae-Won Joh3JiYun Hwang4Gaab Soo Kim5 Department of Anesthesiology and Pain Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea Department of Anesthesiology and Pain Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea Department of Anesthesiology and Pain Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea Department of Anesthesiology and Pain Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea Department of Anesthesiology and Pain Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, KoreaBackground Fontan-associated liver disease (FALD) is a hepatic disorder caused by hemodynamic changes and systemic venous congestion following the Fontan procedure. FALD includes liver cirrhosis and hepatocellular carcinoma (HCC), both of which may require liver transplantation (LT). However, the Fontan circulation, characterized by elevated central venous pressure and reduced cardiac output, is a challenging issue for surgeons and anesthesiologists. Case We report a living-donor LT for the treatment of HCC. The patient was a 24-year-old male who underwent the Fontan procedure for pulmonary atresia and right ventricle hypoplasia. We focused on maintaining enough blood volume for cardiac output without causing pulmonary edema, as the patient is not well adapted to changes in volume. Owing to a multidisciplinary approach, the surgery was successfully performed without fatal adverse events. Conclusions To our knowledge, this is the first case of isolated LT in a recipient who became an adult after having undergone the Fontan procedure.http://www.anesth-pain-med.org/upload/pdf/apm-20037.pdffontan procedurehepatocellular carcinomaliver cirrhosisliver transplantation |
| spellingShingle | Min-kyung Cho Ji-Hye Kwon Mi Sook Gwak Jae-Won Joh JiYun Hwang Gaab Soo Kim Liver transplantation in an adult patient with hepatocellular carcinoma following liver cirrhosis as a complication of the Fontan procedure -A case report- Anesthesia and Pain Medicine fontan procedure hepatocellular carcinoma liver cirrhosis liver transplantation |
| title | Liver transplantation in an adult patient with hepatocellular carcinoma following liver cirrhosis as a complication of the Fontan procedure -A case report- |
| title_full | Liver transplantation in an adult patient with hepatocellular carcinoma following liver cirrhosis as a complication of the Fontan procedure -A case report- |
| title_fullStr | Liver transplantation in an adult patient with hepatocellular carcinoma following liver cirrhosis as a complication of the Fontan procedure -A case report- |
| title_full_unstemmed | Liver transplantation in an adult patient with hepatocellular carcinoma following liver cirrhosis as a complication of the Fontan procedure -A case report- |
| title_short | Liver transplantation in an adult patient with hepatocellular carcinoma following liver cirrhosis as a complication of the Fontan procedure -A case report- |
| title_sort | liver transplantation in an adult patient with hepatocellular carcinoma following liver cirrhosis as a complication of the fontan procedure a case report |
| topic | fontan procedure hepatocellular carcinoma liver cirrhosis liver transplantation |
| url | http://www.anesth-pain-med.org/upload/pdf/apm-20037.pdf |
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