Short term outcomes of extremely low birth weight infants from a multicenter cohort study in Guangdong of China
Abstract With the increase in extremely low birth weight (ELBW) infants, their outcome attracted worldwide attention. However, in China, the related studies are rare. The hospitalized records of ELBW infants discharged from twenty-six neonatal intensive care units in Guangdong Province of China duri...
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-07-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-022-14432-2 |
| _version_ | 1818470970279591936 |
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| author | Chun-Hong Jia Zhou-Shan Feng Xiao-Jun Lin Qi-Liang Cui Sha-Sha Han Ya Jin Guo-Sheng Liu Chuan-Zhong Yang Xiao-Tong Ye Yi-Heng Dai Wei-Yi Liang Xiu-Zhen Ye Jing Mo Lu Ding Ben-Qing Wu Hong-Xiang Chen Chi-Wang Li Zhe Zhang Xiao Rong Wei-Min Huang Wei Shen Bing-Yan Yang Jun-Feng Lv Le-Ying Huo Hui-Wen Huang Hong-Ping Rao Wen-Kang Yan Yong Yang Xue-Jun Ren Dong Liu Fang-Fang Wang Shi-Guang Diao Xiao-Yan Liu Chu-Ming You Qiong Meng Bin Wang Li-Juan Zhang Yu-Ge Huang Dang Ao Wei-Zhong Li Jie-Ling Chen Yan-Ling Chen Wei Li Zhi-Feng Chen Yue-Qin Ding Xiao-Yu Li Yue-Fang Huang Ni-Yang Lin Yang-Fan Cai Zhong-He Wan Yi Ban Bo Bai Guang-Hong Li Yue-Xiu Yan Fan Wu |
| author_facet | Chun-Hong Jia Zhou-Shan Feng Xiao-Jun Lin Qi-Liang Cui Sha-Sha Han Ya Jin Guo-Sheng Liu Chuan-Zhong Yang Xiao-Tong Ye Yi-Heng Dai Wei-Yi Liang Xiu-Zhen Ye Jing Mo Lu Ding Ben-Qing Wu Hong-Xiang Chen Chi-Wang Li Zhe Zhang Xiao Rong Wei-Min Huang Wei Shen Bing-Yan Yang Jun-Feng Lv Le-Ying Huo Hui-Wen Huang Hong-Ping Rao Wen-Kang Yan Yong Yang Xue-Jun Ren Dong Liu Fang-Fang Wang Shi-Guang Diao Xiao-Yan Liu Chu-Ming You Qiong Meng Bin Wang Li-Juan Zhang Yu-Ge Huang Dang Ao Wei-Zhong Li Jie-Ling Chen Yan-Ling Chen Wei Li Zhi-Feng Chen Yue-Qin Ding Xiao-Yu Li Yue-Fang Huang Ni-Yang Lin Yang-Fan Cai Zhong-He Wan Yi Ban Bo Bai Guang-Hong Li Yue-Xiu Yan Fan Wu |
| author_sort | Chun-Hong Jia |
| collection | DOAJ |
| description | Abstract With the increase in extremely low birth weight (ELBW) infants, their outcome attracted worldwide attention. However, in China, the related studies are rare. The hospitalized records of ELBW infants discharged from twenty-six neonatal intensive care units in Guangdong Province of China during 2008–2017 were analyzed. A total of 2575 ELBW infants were enrolled and the overall survival rate was 55.11%. From 2008 to 2017, the number of ELBW infants increased rapidly from 91 to 466, and the survival rate improved steadily from 41.76% to 62.02%. Increased survival is closely related to birth weight (BW), regional economic development, and specialized hospital. The incidence of complications was neonatal respiratory distress syndrome (85.2%), oxygen dependency at 28 days (63.7%), retinopathy of prematurity (39.3%), intraventricular hemorrhage (29.4%), necrotizing enterocolitis (12.0%), and periventricular leukomalacia (8.0%). Among the 1156 nonsurvivors, 90.0% of infants died during the neonatal period (≤ 28 days). A total of 768 ELBW infants died after treatment withdrawal, for reasons of economic and/or poor outcome. The number of ELBW infants is increasing in Guangdong Province of China, and the overall survival rate is improving steadily. |
| first_indexed | 2024-04-13T21:44:38Z |
| format | Article |
| id | doaj.art-aacf2ef4776946e78a875fa78ad29d89 |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-04-13T21:44:38Z |
| publishDate | 2022-07-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-aacf2ef4776946e78a875fa78ad29d892022-12-22T02:28:38ZengNature PortfolioScientific Reports2045-23222022-07-0112111010.1038/s41598-022-14432-2Short term outcomes of extremely low birth weight infants from a multicenter cohort study in Guangdong of ChinaChun-Hong Jia0Zhou-Shan Feng1Xiao-Jun Lin2Qi-Liang Cui3Sha-Sha Han4Ya Jin5Guo-Sheng Liu6Chuan-Zhong Yang7Xiao-Tong Ye8Yi-Heng Dai9Wei-Yi Liang10Xiu-Zhen Ye11Jing Mo12Lu Ding13Ben-Qing Wu14Hong-Xiang Chen15Chi-Wang Li16Zhe Zhang17Xiao Rong18Wei-Min Huang19Wei Shen20Bing-Yan Yang21Jun-Feng Lv22Le-Ying Huo23Hui-Wen Huang24Hong-Ping Rao25Wen-Kang Yan26Yong Yang27Xue-Jun Ren28Dong Liu29Fang-Fang Wang30Shi-Guang Diao31Xiao-Yan Liu32Chu-Ming You33Qiong Meng34Bin Wang35Li-Juan Zhang36Yu-Ge Huang37Dang Ao38Wei-Zhong Li39Jie-Ling Chen40Yan-Ling Chen41Wei Li42Zhi-Feng Chen43Yue-Qin Ding44Xiao-Yu Li45Yue-Fang Huang46Ni-Yang Lin47Yang-Fan Cai48Zhong-He Wan49Yi Ban50Bo Bai51Guang-Hong Li52Yue-Xiu Yan53Fan Wu54Department of Pediatrics, The Third Affiliated Hospital of Guangzhou Medical UniversityDepartment of Pediatrics, The Third Affiliated Hospital of Guangzhou Medical UniversityDepartment of Pediatrics, The Third Affiliated Hospital of Guangzhou Medical UniversityDepartment of Pediatrics, The Third Affiliated Hospital of Guangzhou Medical UniversityDepartment of Neonatology, The First Affiliated Hospital of Jinan UniversityDepartment of Neonatology, The First Affiliated Hospital of Jinan UniversityDepartment of Neonatology, The First Affiliated Hospital of Jinan UniversityDepartment of Neonatology, Shenzhen Maternal and Child Healthcare Hospital, Affiliated Southern Medical UniversityDepartment of Neonatology, Shenzhen Maternal and Child Healthcare Hospital, Affiliated Southern Medical UniversityDepartment of Neonatology, Foshan Maternal and Child’s HospitalDepartment of Neonatology, Foshan Maternal and Child’s HospitalDepartment of Neonatology, Women and Children Hospital of Guangdong ProvinceDepartment of Neonatology, Women and Children Hospital of Guangdong ProvinceDepartment of Neonatology, Shenzhen People’s HospitalDepartment of Neonatology, Shenzhen People’s HospitalDepartment of Neonatology, Meizhou People’s HospitalDepartment of Neonatology, Meizhou People’s HospitalDepartment of Neonatology, Guangzhou Women and Children’s Medical CenterDepartment of Neonatology, Guangzhou Women and Children’s Medical CenterDepartment of Neonatology, Nanfang Hospital of Southern Medical UniversityDepartment of Neonatology, Nanfang Hospital of Southern Medical UniversityDepartment of Neonatology, Boai Hospital of ZhongshanDepartment of Neonatology, Boai Hospital of ZhongshanDepartment of Neonatology, Zhuhai Maternity and Child Health HospitalDepartment of Neonatology, Zhuhai Maternity and Child Health HospitalDepartment of Neonatology, Huizhou Municipal Central HospitalDepartment of Neonatology, Huizhou Municipal Central HospitalDepartment of Neonatology, Dongguan Maternity and Child Health HospitalDepartment of Neonatology, Dongguan Maternity and Child Health HospitalDepartment of Neonatology, Jiangmen Central Hospital, Affiliated Jiangmen Hospital of Sun Yat-Sen UniversityDepartment of Neonatology, Jiangmen Central Hospital, Affiliated Jiangmen Hospital of Sun Yat-Sen UniversityDepartment of Neonatology, Yuebei People’s HospitalDepartment of Neonatology, Yuebei People’s HospitalDepartment of Neonatology, Guangdong Second Provincial People’s HospitalDepartment of Neonatology, Guangdong Second Provincial People’s HospitalDepartment of Pediatrics, Zhujiang Hospital of Southern Medical UniversityDepartment of Pediatrics, Zhujiang Hospital of Southern Medical UniversityDepartment of Pediatrics, The Affiliated Hospital of Guangdong Medical UniversityDepartment of Pediatrics, The Affiliated Hospital of Guangdong Medical UniversityDepartment of Neonatology, The Second Affiliated Hospital of Shantou University Medical CollegeDepartment of Neonatology, The Second Affiliated Hospital of Shantou University Medical CollegeDepartment of Neonatology, Jinan University Medical College Affiliated Dongguan HospitalDepartment of Neonatology, Jinan University Medical College Affiliated Dongguan HospitalDepartment of Pediatrics, Dongguan People’s HospitalDepartment of Pediatrics, Dongguan People’s HospitalDepartment of Neonatology, The First Affiliated Hospital of Sun Yat-Sen UniversityDepartment of Neonatology, The First Affiliated Hospital of Sun Yat-Sen UniversityDepartment of Neonatology, The First Affiliated Hospital of Shantou University Medical CollegeDepartment of Neonatology, The First Affiliated Hospital of Shantou University Medical CollegeDepartment of Neonatology, Nanhai District People’s Hospital of FoshanDepartment of Neonatology, Nanhai District People’s Hospital of FoshanDepartment of Neonatology, Huadu District People’s Hospital of GuangzhouDepartment of Neonatology, Huadu District People’s Hospital of GuangzhouDepartment of Pediatrics, The First People’s Hospital of ZhaoqingDepartment of Pediatrics, The Third Affiliated Hospital of Guangzhou Medical UniversityAbstract With the increase in extremely low birth weight (ELBW) infants, their outcome attracted worldwide attention. However, in China, the related studies are rare. The hospitalized records of ELBW infants discharged from twenty-six neonatal intensive care units in Guangdong Province of China during 2008–2017 were analyzed. A total of 2575 ELBW infants were enrolled and the overall survival rate was 55.11%. From 2008 to 2017, the number of ELBW infants increased rapidly from 91 to 466, and the survival rate improved steadily from 41.76% to 62.02%. Increased survival is closely related to birth weight (BW), regional economic development, and specialized hospital. The incidence of complications was neonatal respiratory distress syndrome (85.2%), oxygen dependency at 28 days (63.7%), retinopathy of prematurity (39.3%), intraventricular hemorrhage (29.4%), necrotizing enterocolitis (12.0%), and periventricular leukomalacia (8.0%). Among the 1156 nonsurvivors, 90.0% of infants died during the neonatal period (≤ 28 days). A total of 768 ELBW infants died after treatment withdrawal, for reasons of economic and/or poor outcome. The number of ELBW infants is increasing in Guangdong Province of China, and the overall survival rate is improving steadily.https://doi.org/10.1038/s41598-022-14432-2 |
| spellingShingle | Chun-Hong Jia Zhou-Shan Feng Xiao-Jun Lin Qi-Liang Cui Sha-Sha Han Ya Jin Guo-Sheng Liu Chuan-Zhong Yang Xiao-Tong Ye Yi-Heng Dai Wei-Yi Liang Xiu-Zhen Ye Jing Mo Lu Ding Ben-Qing Wu Hong-Xiang Chen Chi-Wang Li Zhe Zhang Xiao Rong Wei-Min Huang Wei Shen Bing-Yan Yang Jun-Feng Lv Le-Ying Huo Hui-Wen Huang Hong-Ping Rao Wen-Kang Yan Yong Yang Xue-Jun Ren Dong Liu Fang-Fang Wang Shi-Guang Diao Xiao-Yan Liu Chu-Ming You Qiong Meng Bin Wang Li-Juan Zhang Yu-Ge Huang Dang Ao Wei-Zhong Li Jie-Ling Chen Yan-Ling Chen Wei Li Zhi-Feng Chen Yue-Qin Ding Xiao-Yu Li Yue-Fang Huang Ni-Yang Lin Yang-Fan Cai Zhong-He Wan Yi Ban Bo Bai Guang-Hong Li Yue-Xiu Yan Fan Wu Short term outcomes of extremely low birth weight infants from a multicenter cohort study in Guangdong of China Scientific Reports |
| title | Short term outcomes of extremely low birth weight infants from a multicenter cohort study in Guangdong of China |
| title_full | Short term outcomes of extremely low birth weight infants from a multicenter cohort study in Guangdong of China |
| title_fullStr | Short term outcomes of extremely low birth weight infants from a multicenter cohort study in Guangdong of China |
| title_full_unstemmed | Short term outcomes of extremely low birth weight infants from a multicenter cohort study in Guangdong of China |
| title_short | Short term outcomes of extremely low birth weight infants from a multicenter cohort study in Guangdong of China |
| title_sort | short term outcomes of extremely low birth weight infants from a multicenter cohort study in guangdong of china |
| url | https://doi.org/10.1038/s41598-022-14432-2 |
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