Association between winter season and desmopressin treatment efficiency in children with monosymptomatic nocturnal enuresis: a pilot study
ABSTRACT Objectives: The purpose of our study was to assess the association between the winter season and desmopressin treatment failure in South Chinese children with monosymptomatic nocturnal enuresis (MNE). Materials and Methods: A retrospective study was conducted to analyze the clinical data...
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| Format: | Article |
| Language: | English |
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Sociedade Brasileira de Urologia
2022-03-01
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| Series: | International Brazilian Journal of Urology |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382022000200275&tlng=en |
| _version_ | 1818338617238487040 |
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| author | Mengkui Sun Shoulin Li Xuerui Sun Zhimei Deng Yanan Xu |
| author_facet | Mengkui Sun Shoulin Li Xuerui Sun Zhimei Deng Yanan Xu |
| author_sort | Mengkui Sun |
| collection | DOAJ |
| description | ABSTRACT Objectives: The purpose of our study was to assess the association between the winter season and desmopressin treatment failure in South Chinese children with monosymptomatic nocturnal enuresis (MNE). Materials and Methods: A retrospective study was conducted to analyze the clinical data of children with monosymptomatic nocturnal enuresis who have visited our urology clinic from January to December 2019. All patients received desmopressin treatment. Final treatment outcomes were categorized as successful (complete response) or failed (absent and partial response). The relationship between winter season and treatment response to desmopressin was evaluated. Additionally, associated risk factors were investigated with both univariate and multivariate regression analysis. Results: In total, 393 patients diagnosed with MNE were included in the present study. There were no statistically significant differences in pretreatment variables at first visit between patients who visited the clinic in winter and those who did so in other seasons. However, the treatment failure rate of MNE in the winter season was higher than that of other seasons (77.50% vs. 52.74%). Multivariate logistic regression analysis demonstrated that the severity of symptoms and an initial clinic visit in the winter season were significantly related to desmopressin treatment failure in MNE patients. Conclusion: Winter season and severity of symptoms are two risk factors associated with desmopressin treatment failure in MNE patients. |
| first_indexed | 2024-12-13T15:13:57Z |
| format | Article |
| id | doaj.art-aad0bb8f890c413ea4e80853772bcc1a |
| institution | Directory Open Access Journal |
| issn | 1677-6119 |
| language | English |
| last_indexed | 2024-12-13T15:13:57Z |
| publishDate | 2022-03-01 |
| publisher | Sociedade Brasileira de Urologia |
| record_format | Article |
| series | International Brazilian Journal of Urology |
| spelling | doaj.art-aad0bb8f890c413ea4e80853772bcc1a2022-12-21T23:40:47ZengSociedade Brasileira de UrologiaInternational Brazilian Journal of Urology1677-61192022-03-0148227528110.1590/s1677-5538.ibju.2021.0236Association between winter season and desmopressin treatment efficiency in children with monosymptomatic nocturnal enuresis: a pilot studyMengkui SunShoulin Lihttps://orcid.org/0000-0001-6914-4481Xuerui SunZhimei DengYanan XuABSTRACT Objectives: The purpose of our study was to assess the association between the winter season and desmopressin treatment failure in South Chinese children with monosymptomatic nocturnal enuresis (MNE). Materials and Methods: A retrospective study was conducted to analyze the clinical data of children with monosymptomatic nocturnal enuresis who have visited our urology clinic from January to December 2019. All patients received desmopressin treatment. Final treatment outcomes were categorized as successful (complete response) or failed (absent and partial response). The relationship between winter season and treatment response to desmopressin was evaluated. Additionally, associated risk factors were investigated with both univariate and multivariate regression analysis. Results: In total, 393 patients diagnosed with MNE were included in the present study. There were no statistically significant differences in pretreatment variables at first visit between patients who visited the clinic in winter and those who did so in other seasons. However, the treatment failure rate of MNE in the winter season was higher than that of other seasons (77.50% vs. 52.74%). Multivariate logistic regression analysis demonstrated that the severity of symptoms and an initial clinic visit in the winter season were significantly related to desmopressin treatment failure in MNE patients. Conclusion: Winter season and severity of symptoms are two risk factors associated with desmopressin treatment failure in MNE patients.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382022000200275&tlng=enNocturnal EnuresisTreatment FailureChild |
| spellingShingle | Mengkui Sun Shoulin Li Xuerui Sun Zhimei Deng Yanan Xu Association between winter season and desmopressin treatment efficiency in children with monosymptomatic nocturnal enuresis: a pilot study International Brazilian Journal of Urology Nocturnal Enuresis Treatment Failure Child |
| title | Association between winter season and desmopressin treatment efficiency in children with monosymptomatic nocturnal enuresis: a pilot study |
| title_full | Association between winter season and desmopressin treatment efficiency in children with monosymptomatic nocturnal enuresis: a pilot study |
| title_fullStr | Association between winter season and desmopressin treatment efficiency in children with monosymptomatic nocturnal enuresis: a pilot study |
| title_full_unstemmed | Association between winter season and desmopressin treatment efficiency in children with monosymptomatic nocturnal enuresis: a pilot study |
| title_short | Association between winter season and desmopressin treatment efficiency in children with monosymptomatic nocturnal enuresis: a pilot study |
| title_sort | association between winter season and desmopressin treatment efficiency in children with monosymptomatic nocturnal enuresis a pilot study |
| topic | Nocturnal Enuresis Treatment Failure Child |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382022000200275&tlng=en |
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