ICAM-1-suPAR-CD11b Axis Is a Novel Therapeutic Target for Metastatic Triple-Negative Breast Cancer

ICAM-1-suPAR-CD11b Axis Is a Novel Therapeutic Target for Metastatic Triple-Negative Breast Cancer

Accumulating evidence demonstrates that circulating tumor cell (CTC) clusters have higher metastatic ability than single CTCs and negatively correlate with cancer patient outcomes. Along with homotypic CTC clusters, heterotypic CTC clusters (such as neutrophil–CTC clusters), which have been identifi...

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Bibliographic Details
Main Authors: Dong Li, Hami Hemati, Younhee Park, Rokana Taftaf, Youbin Zhang, Jinpeng Liu, Massimo Cristofanilli, Xia Liu
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Cancers
Subjects:
TNBC
metastasis
neutrophil
soluble uPAR
ICAM-1
CD11b
Online Access:https://www.mdpi.com/2072-6694/15/10/2734

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