A Review of How Lasers Are Used in UTUC Surgery: Can the Choice of Laser Affect Outcomes?
Upper tract urothelial carcinoma (UTUC) is a relatively rare disease with an aggressive phenotype compared to urothelial carcinoma in the bladder. In recent years, kidney-sparing surgery (KSS) and, in particular, endoscopic surgery have become the procedure of choice among urologists where the treat...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-03-01
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| Series: | Cancers |
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| Online Access: | https://www.mdpi.com/2072-6694/15/6/1874 |
| _version_ | 1797612934305677312 |
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| author | Mark Taratkin Nirmish Singla Diana Babaevskaya Alexander Androsov Shahrokh F. Shariat Harun Fajkovic Jack Baniel Dmitry Enikeev |
| author_facet | Mark Taratkin Nirmish Singla Diana Babaevskaya Alexander Androsov Shahrokh F. Shariat Harun Fajkovic Jack Baniel Dmitry Enikeev |
| author_sort | Mark Taratkin |
| collection | DOAJ |
| description | Upper tract urothelial carcinoma (UTUC) is a relatively rare disease with an aggressive phenotype compared to urothelial carcinoma in the bladder. In recent years, kidney-sparing surgery (KSS) and, in particular, endoscopic surgery have become the procedure of choice among urologists where the treatment of localized UTUC is concerned. Endoscopy tends to result in satisfactory oncological disease control while lowering morbidity and minimizing complications amongst the appropriately selected cohort of patients. While endoscopic surgery for UTUC might appear to be standardized, it, in fact, differs considerably depending on the source of energy used for resection/ablation. There has been little reliable data up to now on which laser energy source is the most superior. The goal of this review is, therefore, to outline the results of endoscopic UTUC treatment using different lasers and to analyze how these laser-tissue interactions may affect the surgery. We start by pointing out that the data remains insufficient when trying to determine which laser is the most effective in the endoscopic management of UTUC. The ever-growing number of indications for minimally invasive treatment and the increasing number of centers using laser surgery will, hopefully, lead to novel randomized controlled trials that compare the performance characteristics of the lasers as well as the effects of UTUC on patients. |
| first_indexed | 2024-03-11T06:48:53Z |
| format | Article |
| id | doaj.art-aad3738b684e4751a23c2de6e44ea40e |
| institution | Directory Open Access Journal |
| issn | 2072-6694 |
| language | English |
| last_indexed | 2024-03-11T06:48:53Z |
| publishDate | 2023-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Cancers |
| spelling | doaj.art-aad3738b684e4751a23c2de6e44ea40e2023-11-17T10:08:26ZengMDPI AGCancers2072-66942023-03-01156187410.3390/cancers15061874A Review of How Lasers Are Used in UTUC Surgery: Can the Choice of Laser Affect Outcomes?Mark Taratkin0Nirmish Singla1Diana Babaevskaya2Alexander Androsov3Shahrokh F. Shariat4Harun Fajkovic5Jack Baniel6Dmitry Enikeev7Institute for Urology and Reproductive Health, Sechenov University, 119435 Moscow, RussiaDepartment of Urology, James Buchanan Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USAInstitute for Urology and Reproductive Health, Sechenov University, 119435 Moscow, RussiaInstitute for Clinical Medicine, Sechenov University, 119021 Moscow, RussiaInstitute for Urology and Reproductive Health, Sechenov University, 119435 Moscow, RussiaDepartment of Urology, Medical University of Vienna, 1030 Vienna, AustriaDivision of Urology, Rabin Medical Center, Petach Tikva 4920232, IsraelInstitute for Urology and Reproductive Health, Sechenov University, 119435 Moscow, RussiaUpper tract urothelial carcinoma (UTUC) is a relatively rare disease with an aggressive phenotype compared to urothelial carcinoma in the bladder. In recent years, kidney-sparing surgery (KSS) and, in particular, endoscopic surgery have become the procedure of choice among urologists where the treatment of localized UTUC is concerned. Endoscopy tends to result in satisfactory oncological disease control while lowering morbidity and minimizing complications amongst the appropriately selected cohort of patients. While endoscopic surgery for UTUC might appear to be standardized, it, in fact, differs considerably depending on the source of energy used for resection/ablation. There has been little reliable data up to now on which laser energy source is the most superior. The goal of this review is, therefore, to outline the results of endoscopic UTUC treatment using different lasers and to analyze how these laser-tissue interactions may affect the surgery. We start by pointing out that the data remains insufficient when trying to determine which laser is the most effective in the endoscopic management of UTUC. The ever-growing number of indications for minimally invasive treatment and the increasing number of centers using laser surgery will, hopefully, lead to novel randomized controlled trials that compare the performance characteristics of the lasers as well as the effects of UTUC on patients.https://www.mdpi.com/2072-6694/15/6/1874upper tract urothelial cell carcinoma (UTUC)laser ablationkidney-sparing surgeryendoscopic treatment |
| spellingShingle | Mark Taratkin Nirmish Singla Diana Babaevskaya Alexander Androsov Shahrokh F. Shariat Harun Fajkovic Jack Baniel Dmitry Enikeev A Review of How Lasers Are Used in UTUC Surgery: Can the Choice of Laser Affect Outcomes? Cancers upper tract urothelial cell carcinoma (UTUC) laser ablation kidney-sparing surgery endoscopic treatment |
| title | A Review of How Lasers Are Used in UTUC Surgery: Can the Choice of Laser Affect Outcomes? |
| title_full | A Review of How Lasers Are Used in UTUC Surgery: Can the Choice of Laser Affect Outcomes? |
| title_fullStr | A Review of How Lasers Are Used in UTUC Surgery: Can the Choice of Laser Affect Outcomes? |
| title_full_unstemmed | A Review of How Lasers Are Used in UTUC Surgery: Can the Choice of Laser Affect Outcomes? |
| title_short | A Review of How Lasers Are Used in UTUC Surgery: Can the Choice of Laser Affect Outcomes? |
| title_sort | review of how lasers are used in utuc surgery can the choice of laser affect outcomes |
| topic | upper tract urothelial cell carcinoma (UTUC) laser ablation kidney-sparing surgery endoscopic treatment |
| url | https://www.mdpi.com/2072-6694/15/6/1874 |
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