Cell type-specific transcriptional programs in mouse prefrontal cortex during adolescence and addiction
Cognitive behaviours are encoded and regulated by coordinated activity-induced transcriptional changes. Through single-cell RNA sequencing, the authors classify diverse cell types in mouse prefrontal cortex and analyze their transcriptional adaptations in adolescence and drug addiction.
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2019-09-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-019-12054-3 |
| _version_ | 1819035834788085760 |
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| author | Aritra Bhattacherjee Mohamed Nadhir Djekidel Renchao Chen Wenqiang Chen Luis M. Tuesta Yi Zhang |
| author_facet | Aritra Bhattacherjee Mohamed Nadhir Djekidel Renchao Chen Wenqiang Chen Luis M. Tuesta Yi Zhang |
| author_sort | Aritra Bhattacherjee |
| collection | DOAJ |
| description | Cognitive behaviours are encoded and regulated by coordinated activity-induced transcriptional changes. Through single-cell RNA sequencing, the authors classify diverse cell types in mouse prefrontal cortex and analyze their transcriptional adaptations in adolescence and drug addiction. |
| first_indexed | 2024-12-21T07:55:56Z |
| format | Article |
| id | doaj.art-aad9d39ab4684044881d90f446251d86 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-21T07:55:56Z |
| publishDate | 2019-09-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-aad9d39ab4684044881d90f446251d862022-12-21T19:10:59ZengNature PortfolioNature Communications2041-17232019-09-0110111810.1038/s41467-019-12054-3Cell type-specific transcriptional programs in mouse prefrontal cortex during adolescence and addictionAritra Bhattacherjee0Mohamed Nadhir Djekidel1Renchao Chen2Wenqiang Chen3Luis M. Tuesta4Yi Zhang5Howard Hughes Medical Institute, Boston Children’s HospitalHoward Hughes Medical Institute, Boston Children’s HospitalHoward Hughes Medical Institute, Boston Children’s HospitalHoward Hughes Medical Institute, Boston Children’s HospitalHoward Hughes Medical Institute, Boston Children’s HospitalHoward Hughes Medical Institute, Boston Children’s HospitalCognitive behaviours are encoded and regulated by coordinated activity-induced transcriptional changes. Through single-cell RNA sequencing, the authors classify diverse cell types in mouse prefrontal cortex and analyze their transcriptional adaptations in adolescence and drug addiction.https://doi.org/10.1038/s41467-019-12054-3 |
| spellingShingle | Aritra Bhattacherjee Mohamed Nadhir Djekidel Renchao Chen Wenqiang Chen Luis M. Tuesta Yi Zhang Cell type-specific transcriptional programs in mouse prefrontal cortex during adolescence and addiction Nature Communications |
| title | Cell type-specific transcriptional programs in mouse prefrontal cortex during adolescence and addiction |
| title_full | Cell type-specific transcriptional programs in mouse prefrontal cortex during adolescence and addiction |
| title_fullStr | Cell type-specific transcriptional programs in mouse prefrontal cortex during adolescence and addiction |
| title_full_unstemmed | Cell type-specific transcriptional programs in mouse prefrontal cortex during adolescence and addiction |
| title_short | Cell type-specific transcriptional programs in mouse prefrontal cortex during adolescence and addiction |
| title_sort | cell type specific transcriptional programs in mouse prefrontal cortex during adolescence and addiction |
| url | https://doi.org/10.1038/s41467-019-12054-3 |
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