Jaccoud’s arthropathy, an unusual manifestation of idiopathic retroperitoneal fibrosis: rapid improvement of symptoms after tocilizumab treatment
Jaccoud’s arthropathy (JA) is a chronic, non erosive, rheumatoid-like deformity associated with rheumatic fever (RF) and systemic lupus erythematosus and with other diseases such as psoriatic arthritis, connective tissue diseases, hypocomplementemic urticarial vasculitis, infections, sarcoidosis and...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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PAGEPress Publications
2017-08-01
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| Series: | Reumatismo |
| Subjects: | |
| Online Access: | http://www.reumatismo.org/index.php/reuma/article/view/968 |
| _version_ | 1818007750001557504 |
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| author | M. Benucci A. Damiani F. Li Gobbi V. Grossi M. Infantino A. Arena M. Manfredi |
| author_facet | M. Benucci A. Damiani F. Li Gobbi V. Grossi M. Infantino A. Arena M. Manfredi |
| author_sort | M. Benucci |
| collection | DOAJ |
| description | Jaccoud’s arthropathy (JA) is a chronic, non erosive, rheumatoid-like deformity associated with rheumatic fever (RF) and systemic lupus erythematosus and with other diseases such as psoriatic arthritis, connective tissue diseases, hypocomplementemic urticarial vasculitis, infections, sarcoidosis and neoplasia. We described a case of JA in a patient with cutaneous psoriasis but with a particular disease evolution associated with idiopathic retropritoneal fibrosis (IRF), evaluated with computed tomography, magnetic resonance and 18F-FDG PET/ CT. The patient, following failure with steroids, methotrexate and etanercept, was treated with tocilizumab (8 mg/kg) once every 4 weeks for 6 months. A rapid improvement of symptoms and disappearance of 18F-FDG uptake was shown. We describe a review of literature of rheumatic manifestations of IRF and the possible role of interleukin-6 in the pathway of JA and IRF. |
| first_indexed | 2024-04-14T05:19:51Z |
| format | Article |
| id | doaj.art-aaddeb4fdd794222896ad79cdd7bdf63 |
| institution | Directory Open Access Journal |
| issn | 0048-7449 2240-2683 |
| language | English |
| last_indexed | 2024-04-14T05:19:51Z |
| publishDate | 2017-08-01 |
| publisher | PAGEPress Publications |
| record_format | Article |
| series | Reumatismo |
| spelling | doaj.art-aaddeb4fdd794222896ad79cdd7bdf632022-12-22T02:10:14ZengPAGEPress PublicationsReumatismo0048-74492240-26832017-08-01692889110.4081/reumatismo.2017.968745Jaccoud’s arthropathy, an unusual manifestation of idiopathic retroperitoneal fibrosis: rapid improvement of symptoms after tocilizumab treatmentM. Benucci0A. Damiani1F. Li Gobbi2V. Grossi3M. Infantino4A. Arena5M. Manfredi6Rheumatology Unit, San Giovanni di Dio Hospital, FlorenceRheumatology Unit, San Giovanni di Dio Hospital, FlorenceRheumatology Unit, San Giovanni di Dio Hospital, FlorenceImmunology and Allergology Laboratory, San Giovanni di Dio Hospital, FlorenceImmunology and Allergology Laboratory, San Giovanni di Dio Hospital, FlorenceNuclear Medicine, New Hospital, PratoImmunology and Allergology Laboratory, San Giovanni di Dio Hospital, FlorenceJaccoud’s arthropathy (JA) is a chronic, non erosive, rheumatoid-like deformity associated with rheumatic fever (RF) and systemic lupus erythematosus and with other diseases such as psoriatic arthritis, connective tissue diseases, hypocomplementemic urticarial vasculitis, infections, sarcoidosis and neoplasia. We described a case of JA in a patient with cutaneous psoriasis but with a particular disease evolution associated with idiopathic retropritoneal fibrosis (IRF), evaluated with computed tomography, magnetic resonance and 18F-FDG PET/ CT. The patient, following failure with steroids, methotrexate and etanercept, was treated with tocilizumab (8 mg/kg) once every 4 weeks for 6 months. A rapid improvement of symptoms and disappearance of 18F-FDG uptake was shown. We describe a review of literature of rheumatic manifestations of IRF and the possible role of interleukin-6 in the pathway of JA and IRF.http://www.reumatismo.org/index.php/reuma/article/view/968Jaccoud’s arthropathyIdiopathic Retroperitoneal fibrosisTocilizumab. |
| spellingShingle | M. Benucci A. Damiani F. Li Gobbi V. Grossi M. Infantino A. Arena M. Manfredi Jaccoud’s arthropathy, an unusual manifestation of idiopathic retroperitoneal fibrosis: rapid improvement of symptoms after tocilizumab treatment Reumatismo Jaccoud’s arthropathy Idiopathic Retroperitoneal fibrosis Tocilizumab. |
| title | Jaccoud’s arthropathy, an unusual manifestation of idiopathic retroperitoneal fibrosis: rapid improvement of symptoms after tocilizumab treatment |
| title_full | Jaccoud’s arthropathy, an unusual manifestation of idiopathic retroperitoneal fibrosis: rapid improvement of symptoms after tocilizumab treatment |
| title_fullStr | Jaccoud’s arthropathy, an unusual manifestation of idiopathic retroperitoneal fibrosis: rapid improvement of symptoms after tocilizumab treatment |
| title_full_unstemmed | Jaccoud’s arthropathy, an unusual manifestation of idiopathic retroperitoneal fibrosis: rapid improvement of symptoms after tocilizumab treatment |
| title_short | Jaccoud’s arthropathy, an unusual manifestation of idiopathic retroperitoneal fibrosis: rapid improvement of symptoms after tocilizumab treatment |
| title_sort | jaccoud s arthropathy an unusual manifestation of idiopathic retroperitoneal fibrosis rapid improvement of symptoms after tocilizumab treatment |
| topic | Jaccoud’s arthropathy Idiopathic Retroperitoneal fibrosis Tocilizumab. |
| url | http://www.reumatismo.org/index.php/reuma/article/view/968 |
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