The prophylactic treatment of Egyptian, Trigonella foenum - graecum L., Extract in comparison to pure diosgenin on experimentally induced non-alcoholic steatohepatitis: New targets via AMPK, RAR, and FXR pathways

The prophylactic treatment of Egyptian, Trigonella foenum - graecum L., Extract in comparison to pure diosgenin on experimentally induced non-alcoholic steatohepatitis: New targets via AMPK, RAR, and FXR pathways

Background: Non-alcoholic steatohepatitis (NASH) is an inflammatory liver condition that damages the liver by accumulating fat. Aim: Our study sought to explore the mechanisms involved through which fengreek, Trigonella foenum - graecum L., extract (FE) or diosgenin (DSG) exerted their hepatoprotect...

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Bibliographic Details
Main Authors: Manar M. Eltamalawy, A.F. Abdel-Aziz, Tarek M. Mohamed, Naglaa F. Khedr
Format: Article
Language:English
Published: Elsevier 2023-05-01
Series:Phytomedicine Plus
Subjects:
Acetyl-CoA carboxylase
Diosgenin
Farnesoid X receptor
Fenugreek
Non-alcoholic steatohepatitis
Retinoic acid receptor
Online Access:http://www.sciencedirect.com/science/article/pii/S2667031323000179

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