Minocycline modulates NFκB phosphorylation and enhances antimicrobial activity against Staphylococcus aureus in mesenchymal stromal/stem cells

Minocycline modulates NFκB phosphorylation and enhances antimicrobial activity against Staphylococcus aureus in mesenchymal stromal/stem cells

Abstract Background Mesenchymal stromal/stem cells (MSCs) have demonstrated pro-healing properties due to their anti-inflammatory, angiogenic, and even antibacterial properties. We have shown previously that minocycline enhances the wound healing phenotype of MSCs, and MSCs encapsulated in poly(ethy...

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Bibliographic Details
Main Authors: Alberto Daniel Guerra, Warren E. Rose, Peiman Hematti, W. John Kao
Format: Article
Language:English
Published: BMC 2017-07-01
Series:Stem Cell Research & Therapy
Subjects:
Mesenchymal stromal cells
Mesenchymal stem cells
Biomaterials
Minocycline
NFκB
Antimicrobial
Online Access:http://link.springer.com/article/10.1186/s13287-017-0623-1

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