Malignant rectal GIST managed with chemotherapy (Imatinib Mesylate): A case report and a comprehensive review
Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors involving the gastrointestinal tract, arising from the interstitial cells of Cajal. GIST comprises about 1% of all GI tumors. Rectal GISTs are rare and comprise of approximately 5% of all GISTs and only 0.1% of rectal tum...
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| Format: | Article |
| Language: | English |
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Elsevier
2024-04-01
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| Series: | Radiology Case Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1930043323009597 |
| _version_ | 1827339755760648192 |
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| author | Amrit Bhusal Suraj KC Tek Nath Yogi Rakesh Kumar Gupta Abhijeet Kumar Bhawani Khanal Shailendra Katwal Durga Neupane Samikshya Lamichhane Ranjan Bhagat |
| author_facet | Amrit Bhusal Suraj KC Tek Nath Yogi Rakesh Kumar Gupta Abhijeet Kumar Bhawani Khanal Shailendra Katwal Durga Neupane Samikshya Lamichhane Ranjan Bhagat |
| author_sort | Amrit Bhusal |
| collection | DOAJ |
| description | Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors involving the gastrointestinal tract, arising from the interstitial cells of Cajal. GIST comprises about 1% of all GI tumors. Rectal GISTs are rare and comprise of approximately 5% of all GISTs and only 0.1% of rectal tumors are found to be GISTs. Rectal GISTs may be diagnosed incidentally or present with symptoms, including defecation problems, bleeding, and/or pain. We report a case of a 46-year-old male with rectal GIST metastasized to the liver and bilateral lung parenchyma managed by Imatinib Mesylate (IM) regimen. Rectal GIST although being rare, must be considered as a differential diagnosis in a patient presenting with defecatory problems with bleeding. |
| first_indexed | 2024-03-07T20:05:20Z |
| format | Article |
| id | doaj.art-aae39a4e59d94b219d976acc5f6d9efc |
| institution | Directory Open Access Journal |
| issn | 1930-0433 |
| language | English |
| last_indexed | 2024-03-07T20:05:20Z |
| publishDate | 2024-04-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Radiology Case Reports |
| spelling | doaj.art-aae39a4e59d94b219d976acc5f6d9efc2024-02-28T05:13:00ZengElsevierRadiology Case Reports1930-04332024-04-0119414241431Malignant rectal GIST managed with chemotherapy (Imatinib Mesylate): A case report and a comprehensive reviewAmrit Bhusal0Suraj KC1Tek Nath Yogi2Rakesh Kumar Gupta3Abhijeet Kumar4Bhawani Khanal5Shailendra Katwal6Durga Neupane7Samikshya Lamichhane8Ranjan Bhagat9Department of Radio-diagnostics and Imaging, BP Koirala Institute of Health Sciences (BPKIHS), Dharan, Sunsari, Nepal; Corresponding author.Department of General Surgery, BP Koirala Institute of Health Sciences (BPKIHS), Dharan, Sunsari, NepalBP Koirala Institute of Health Sciences (BPKIHS), Dharan, Sunsari, NepalDepartment of General Surgery, BP Koirala Institute of Health Sciences (BPKIHS), Dharan, Sunsari, NepalDepartment of General Surgery, BP Koirala Institute of Health Sciences (BPKIHS), Dharan, Sunsari, NepalDepartment of General Surgery, BP Koirala Institute of Health Sciences (BPKIHS), Dharan, Sunsari, NepalDepartment of Radiology, Dadeldhura Subregional Hospital, Dadeldhura, NepalDepartment of General Surgery, BP Koirala Institute of Health Sciences (BPKIHS), Dharan, Sunsari, NepalDepartment of Radio-diagnostics and Imaging, BP Koirala Institute of Health Sciences (BPKIHS), Dharan, Sunsari, NepalDepartment of General Surgery, BP Koirala Institute of Health Sciences (BPKIHS), Dharan, Sunsari, NepalGastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors involving the gastrointestinal tract, arising from the interstitial cells of Cajal. GIST comprises about 1% of all GI tumors. Rectal GISTs are rare and comprise of approximately 5% of all GISTs and only 0.1% of rectal tumors are found to be GISTs. Rectal GISTs may be diagnosed incidentally or present with symptoms, including defecation problems, bleeding, and/or pain. We report a case of a 46-year-old male with rectal GIST metastasized to the liver and bilateral lung parenchyma managed by Imatinib Mesylate (IM) regimen. Rectal GIST although being rare, must be considered as a differential diagnosis in a patient presenting with defecatory problems with bleeding.http://www.sciencedirect.com/science/article/pii/S1930043323009597Gastrointestinal stromal tumorsRectal tumorsMetastasisRareImatinib MesylateCase report |
| spellingShingle | Amrit Bhusal Suraj KC Tek Nath Yogi Rakesh Kumar Gupta Abhijeet Kumar Bhawani Khanal Shailendra Katwal Durga Neupane Samikshya Lamichhane Ranjan Bhagat Malignant rectal GIST managed with chemotherapy (Imatinib Mesylate): A case report and a comprehensive review Radiology Case Reports Gastrointestinal stromal tumors Rectal tumors Metastasis Rare Imatinib Mesylate Case report |
| title | Malignant rectal GIST managed with chemotherapy (Imatinib Mesylate): A case report and a comprehensive review |
| title_full | Malignant rectal GIST managed with chemotherapy (Imatinib Mesylate): A case report and a comprehensive review |
| title_fullStr | Malignant rectal GIST managed with chemotherapy (Imatinib Mesylate): A case report and a comprehensive review |
| title_full_unstemmed | Malignant rectal GIST managed with chemotherapy (Imatinib Mesylate): A case report and a comprehensive review |
| title_short | Malignant rectal GIST managed with chemotherapy (Imatinib Mesylate): A case report and a comprehensive review |
| title_sort | malignant rectal gist managed with chemotherapy imatinib mesylate a case report and a comprehensive review |
| topic | Gastrointestinal stromal tumors Rectal tumors Metastasis Rare Imatinib Mesylate Case report |
| url | http://www.sciencedirect.com/science/article/pii/S1930043323009597 |
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