GW5074 Increases Microglial Phagocytic Activities: Potential Therapeutic Direction for Alzheimer’s Disease

GW5074 Increases Microglial Phagocytic Activities: Potential Therapeutic Direction for Alzheimer’s Disease

Microglia, the resident immune cells of the central nervous system (CNS), are responsible for maintaining homeostasis in the brain by clearing debris and are suggested to be inefficient in Alzheimer’s Disease (AD), a progressive neurodegenerative disorder for which there is no disease-modifying drug...

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Bibliographic Details
Main Authors:	Sarah M. Connor, Mamunur Rashid, Katie J. Ryan, Kruti Patel, Justin D. Boyd, Jennifer Smith, Wassim Elyaman, David A. Bennett, Elizabeth M. Bradshaw
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-05-01
Series:	Frontiers in Cellular Neuroscience
Subjects:	Alzheimer’s disease microglia GW5074 c-RAF high content drug screening TREM2
Online Access:	https://www.frontiersin.org/articles/10.3389/fncel.2022.894601/full

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